Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.30 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.30 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140811 | 0.78 | HSD17B10 (0.43) | HSD17B10KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL10118778 | 0.78 | HSD17B10 (0.43) | HSD17B10KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL22533975 | 0.76 | PRMT5 (0.42) | HSD17B10KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL29424830 | 0.76 | PRMT5 (0.42) | HSD17B10KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL12231815 | 0.76 | DDAH1 (0.48) | ADORA3ADORA2AADORA1HTTDDAH1 | |
| SCHEMBL12232006 | 0.74 | KDM4E (0.40) | HSD17B10KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL29543491 | 0.72 | KDM4E (0.39) | HSD17B10KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL12810051 | 0.72 | HSD17B10 (0.36) | HSD17B10KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL22533874 | 0.70 | CHEK2 (0.46) | HSD17B10KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL805162 | 0.69 | NUDT1 (0.55) | HSD17B10KDM4ELMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | HSD17B10 1268/4885KDM4E 4219/4885LMNA 2015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.