Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25833262 | 0.87 | SLC6A2 (0.34) | — | |
| SCHEMBL2393968 | 0.84 | ALDH1A1 (0.32) | — | |
| SCHEMBL16224877 | 0.78 | AOC3 (0.42) | IDO1TDO2AOC3 | |
| SCHEMBL17086661 | 0.78 | AOC3 (0.42) | IDO1TDO2AOC3 | |
| SCHEMBL17086659 | 0.78 | AOC3 (0.42) | IDO1TDO2AOC3 | |
| SCHEMBL12891861 | 0.77 | USP2 (0.31) | — | |
| SCHEMBL10244197 | 0.75 | USP2 (0.44) | CES2CES1 | |
| SCHEMBL10244133 | 0.75 | USP2 (0.44) | CES2CES1 | |
| SCHEMBL15445117 | 0.75 | USP2 (0.44) | CES2CES1 | |
| SCHEMBL16770966 | 0.74 | SLC6A2 (0.36) | IDO1TDO2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227451-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227451-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | MAPKAPK2, MAPK1, MAPK7 | IDO1 917/4885TDO2 2261/4885CES2 2735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.