SCHEMBL2393968

SCHEMBL2393968

COCC(C)c1cc(C(C)COC)cc(C(C)COC)c1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP2D6 P10635 1/20 0.32
ABCB11 O95342 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28054380 0.85
SCHEMBL6058434 0.85 HMGCR (0.33)
SCHEMBL25833637 0.84 IDO1 (0.32)
SCHEMBL17071865 0.84 SLC6A2 (0.36) ALDH1A1
SCHEMBL16770966 0.84 SLC6A2 (0.36) ALDH1A1
SCHEMBL16770758 0.84 SLC6A2 (0.36) ALDH1A1
SCHEMBL6058476 0.83 L3MBTL1 (0.38) ALDH1A1ABCB11L3MBTL1
SCHEMBL2093765 0.77 TAAR1 (0.54) ALDH1A1
SCHEMBL1911097 0.77 TAAR1 (0.54) ALDH1A1
SCHEMBL12282802 0.77 TAAR1 (0.54) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10875955-B2 Initiators for living carbocationic polymerization The University of Akron , Ohio (US) 2020-12-29 US disclosed
US-10472457-B2 Initiators for living carbocationic polymerization THE UNIVERSITY OF AKRON (US) 2019-11-12 US disclosed
EP-2099831-B1 POLYISOBUTYLENES AND PROCESS FOR MAKING SAME UNIV AKRON (US) 2019-07-31 EP disclosed
US-20190127510-A1 NOVEL INITIATORS FOR LIVING CARBOCATIONIC POLYMERIZATION THE UNIVERSITY OF AKRON (US) 2019-05-02 US disclosed
US-10005852-B2 Polyisobutylenes and process for making same THE UNIVERSITY OF AKRON (US) 2018-06-26 US disclosed
US-20180066079-A1 POLYISOBUTYLENES AND PROCESS FOR MAKING SAME THE UNIVERSITY OF AKRON (US) 2018-03-08 US disclosed
US-9834622-B2 Polyisobutylenes and process for making same THE UNIVERSITY OF AKRON (US) 2017-12-05 US disclosed
US-20170174796-A1 POLYISOBUTYLENES AND PROCESS FOR MAKING SAME UNIV AKRON (US) 2017-06-22 US disclosed
US-9587067-B2 Polyisobutylenes and process for making same THE UNIVERSITY OF AKRON (US) 2017-03-07 US disclosed
US-9359465-B2 Polyisobutylenes and process for making same THE UNIVERSITY OF AKRON (US) 2016-06-07 US disclosed
EP-2155107-B1 INJECTIBLE CYANOACRYLATE-FUNCTIONALIZED POLYISOBUTYLENES UNIV AKRON (US) 2016-04-13 EP disclosed
US-20160090437-A1 POLYISOBUTYLENES AND PROCESS FOR MAKING SAME THE UNIVERSITY OF AKRON (US) 2016-03-31 US disclosed
US-20140005349-A1 POLYISOBUTYLENES AND PROCESS FOR MAKING SAME THE UNIVERSITY OF AKRON (US) 2014-01-02 US disclosed
US-8552118-B2 Polyisobutylenes and process for making same THE UNIVERSITY OF AKRON (US) 2013-10-08 US disclosed
US-8431666-B2 Injectible cyanoacrylate-functionalized polyisobutylenes THE UNIVERSITY OF AKRON (US) 2013-04-30 US disclosed
US-20130041108-A1 POLYMERS HAVING BOTH HARD AND SOFT SEGMENTS, AND PROCESS FOR MAKING SAME KENNEDY JOSEPH P (US) 2013-02-14 US disclosed
EP-2474563-A1 Polyisobutylene-based polyurethane and polyurea The University of Akron (US) 2012-07-11 EP disclosed
US-20110213084-A1 POLYMERS HAVING BOTH HARD AND SOFT SEGMENTS, AND PROCESS FOR MAKING SAME THE UNIVERSITY OF AKRON (US) 2011-09-01 US disclosed
US-20100144996-A1 INJECTIBLE CYANOACRYLATE-FUNCTIONALIZED POLYISOBUTYLENES THE UNIVERSITY OF AKRON (US) 2010-06-10 US disclosed
US-20100130696-A1 POLYISOBUTYLENES AND PROCESS FOR MAKING SAME THE UNIVERSITY OF AKRON (US) 2010-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140005349-A1 POLYISOBUTYLENES AND PROCESS FOR MAKING SAME ALKBH3, ALKBH5, PARG ALDH1A1 72/4885KDM4E 177/4885CYP2D6 2956/4885
US-10875955-B2 Initiators for living carbocationic polymerization ICMT, CTH, TST ALDH1A1 1635/4885KDM4E 1010/4885CYP2D6 3262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.