SCHEMBL25833727

SCHEMBL25833727

N=C1CCC2(CCCO2)CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136849 0.76 CYP11B1 (0.31) CYP11B1CYP11B2
SCHEMBL14721344 0.76 KCNH2 (0.32) CYP11B1CYP11B2
SCHEMBL134965 0.76 TRIM24 (0.35) CYP11B1CYP11B2
SCHEMBL126707 0.76
SCHEMBL127016 0.76
SCHEMBL126686 0.76
SCHEMBL3505574 0.73 KCNH2 (0.33) CYP11B1CYP11B2
SCHEMBL320777 0.73 KCNH2 (0.33) CYP11B1CYP11B2
SCHEMBL1811309 0.73 KCNH2 (0.33) CYP11B1CYP11B2
SCHEMBL1813694 0.73 TRIM24 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125907-A1 DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE BEIGENE, LTD. (KY) 2023-07-06 WO disclosed