Norharmane

Norharmane

SCHEMBL25834

c1ccc2c(c1)[nH]c1cnccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHUK O15111 7/20 1.00
GABRA1 P14867 2/20 1.00
GABRG2 P18507 2/20 1.00
GABRB3 P28472 2/20 1.00
GABRA5 P31644 2/20 1.00
GABRA3 P34903 2/20 1.00
GABRA2 P47869 2/20 1.00
ALDH1A1 P00352 2/20 1.00
KDM4E B2RXH2 1/20 1.00
GABRP O00591 1/20 1.00
GABRD O14764 1/20 1.00
IKBKB O14920 1/20 1.00
AURKA O14965 1/20 1.00
PIM1 P11309 1/20 1.00
TOP1 P11387 1/20 1.00
IDO1 P14902 1/20 1.00
HPGD P15428 1/20 1.00
GABRB1 P18505 1/20 1.00
MAOA P21397 1/20 1.00
MAOB P27338 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Norharmane SCHEMBL29370219 1.00 CHUK (1.00) CHUKGABRA1GABRG2GABRB3GABRA5
Norharmane SCHEMBL9486853 1.00 CHUK (1.00) CHUKGABRA1GABRG2GABRB3GABRA5
Carbazole SCHEMBL18684843 1.00 CHUK (1.00) CHUKGABRA1GABRG2GABRB3GABRA5
Norharmane SCHEMBL11561251 0.98 CHUK (0.96) CHUKGABRA1GABRG2GABRB3GABRA5
Norharmane SCHEMBL21378153 0.98 CHUK (0.96) CHUKGABRA1GABRG2GABRB3GABRA5
Norharmane SCHEMBL8683826 0.98 CHUK (0.96) CHUKGABRA1GABRG2GABRB3GABRA5
Norharmane SCHEMBL30013210 0.98 CHUK (0.96) CHUKGABRA1GABRG2GABRB3GABRA5
Norharmane SCHEMBL8686167 0.98 CHUK (0.96) CHUKGABRA1GABRG2GABRB3GABRA5
Norharmane SCHEMBL29809643 0.98 CHUK (0.96) CHUKGABRA1GABRG2GABRB3GABRA5
Norharmane SCHEMBL29217000 0.98 CHUK (0.96) CHUKGABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13950 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431371-B Beta-carbolin 3,6, 9-modified derivative and preparation method and application thereof 沈阳药科大学 2026-05-19 CN claimed
CN-117186133-B Carboline-fluorobopyrrole photosensitizer and preparation and application thereof in resisting breast cancer 浙江大学 2026-05-19 CN claimed
CN-119688896-B Cell membrane bionic nano-recognition material and preparation method and application thereof 陕西科技大学 2026-05-12 CN claimed
EP-4716472-A1 POUCHED PRODUCT AND METHOD OF MAKING Imperial Tobacco Limited (GB) 2026-04-01 EP claimed
US-20250360150-A1 METHODS OF USING NEUROPLASTIC AGENTS AND TERRAFORMING MARS BRANNOCK METCALF MOLLY CAROLINE (US) 2025-11-27 US claimed
EP-4646432-A1 ANTI-IL-18BP ANTIBODIES Lassen Therapeutics, Inc. (US) 2025-11-12 EP claimed
EP-4646433-A1 ANTI-IL-18BP ANTIBODIES Lassen Therapeutics, Inc. (US) 2025-11-12 EP claimed
EP-4633638-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) Luminous Mind Inc. (US) 2025-10-22 EP claimed
US-20250281399-A1 A MUCOADHESIVE FILM COMPRISING A PHARMACEUTICALLY ACTIVE AGENT AND USES THEREOF SHORT WAVE PHARMA INC. (CA) 2025-09-11 US claimed
US-20250188170-A1 COMPOSITIONS AND METHODS COMPRISING ANTI-NRP2b ANTIBODIES ATYR PHARMA, INC. 2025-06-12 US claimed
US-4644062-A WITH TERT-BUTYL HYPOCHLORITE AND TERTIARY AMINE SCHERING AKTIENGESELLSCHAFT (DE) 1987-02-17 US claimed
US-4623649-A PSYCHOPHARMACEUTICALS SCHERING AKTIENGESELLSCHAFT (DE) 1986-11-18 US claimed
EP-0039804-B1 CYCLIC AMIDES USV PHARMACEUTICAL CORPORATION (US) 1986-08-20 EP claimed
US-4600715-A CENTRAL NERVOUS SYSTEM SHERING AKTIENGESELLSCHAFT (DE) 1986-07-15 US claimed
US-4596808-A Nervous system disorders SCHERING AKTIENGESELLSCHAFT (DE) 1986-06-24 US claimed
EP-0059817-B1 SERPENTINE, ALSTONINE AND SEMPERVIRINE DRUGS FOR THE SPECIFIC INHIBITION OF TUMUROUS AND CANCEROUS CELLS Beljanski, Mirko (FR) 1985-10-09 EP claimed
EP-0110813-A2 Process for producing beta-carboline derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1984-06-13 EP claimed
US-4435403-A TRANQUILIZERS SCHERING AKTIENGESELLSCHAFT (DE) 1984-03-06 US claimed
EP-0059817-A1 Serpentine, alstonine and sempervirine drugs for the specific inhibition of tumurous and cancerous cells Beljanski, Mirko (FR) 1982-09-15 EP claimed
EP-0054507-A2 3-Substituted beta-carbolines, process for their production and compositions containing them SCHERING AKTIENGESELLSCHAFT (DE) 1982-06-23 EP claimed