Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | VNN1 | O95497 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 5/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25342374 | 0.84 | VNN1 (0.50) | HPGDSMN1; SMN2VNN1GRM5ADRA1A | |
| SCHEMBL30589658 | 0.84 | VNN1 (0.50) | HPGDSMN1; SMN2VNN1GRM5ADRA1A | |
| SCHEMBL3242724 | 0.83 | RAB9A (0.65) | RAB9AHPGDSMN1; SMN2GRM5NAPRT | |
| SCHEMBL31392086 | 0.83 | RAB9A (0.65) | RAB9AHPGDSMN1; SMN2GRM5NAPRT | |
| SCHEMBL423224 | 0.83 | RAB9A (0.65) | RAB9AHPGDSMN1; SMN2GRM5NAPRT | |
| SCHEMBL16345854 | 0.82 | VNN1 (0.49) | HPGDSMN1; SMN2VNN1GRM5ADRA1A | |
| SCHEMBL24185705 | 0.82 | RAB9A (0.53) | RAB9AHPGDSMN1; SMN2GRM5NAPRT | |
| SCHEMBL20460596 | 0.81 | GRM5 (0.63) | RAB9AHPGDSMN1; SMN2GRM5NAPRT | |
| SCHEMBL990908 | 0.81 | GRM5 (0.63) | RAB9AHPGDSMN1; SMN2GRM5NAPRT | |
| SCHEMBL28477730 | 0.80 | RAB9A (0.62) | RAB9AHPGDSMN1; SMN2GRM5NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137356-A1 | 15-PGDH INHIBITORS | VENTYX BIOSCIENCES, INC. (US) | 2023-07-20 | — | — | WO | disclosed |