Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498959 | 0.81 | DDB1 (0.44) | DDB1CRBNBRD4SMN1; SMN2ALDH1A1 | |
| SCHEMBL1499114 | 0.81 | DDB1 (0.44) | DDB1CRBNBRD4SMN1; SMN2ALDH1A1 | |
| SCHEMBL1421037 | 0.79 | BRD4 (0.59) | BRD4SMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11191557 | 0.79 | ALDH1A1 (0.45) | DDB1CRBNBRD4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9295153 | 0.78 | BRD4 (0.50) | DDB1CRBNBRD4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6247618 | 0.78 | BRD4 (0.50) | DDB1CRBNBRD4SMN1; SMN2ALDH1A1 | |
| SCHEMBL157619 | 0.78 | BRD4 (0.50) | DDB1CRBNBRD4SMN1; SMN2ALDH1A1 | |
| SCHEMBL4971631 | 0.70 | DDB1 (0.49) | DDB1CRBNSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL9711479 | 0.70 | MAPT (0.52) | DDB1CRBNBRD4SMN1; SMN2ALDH1A1 | |
| SCHEMBL5179397 | 0.69 | SMN1; SMN2 (0.43) | DDB1CRBNBRD4SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226035-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226035-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | CD4, CRBN, GZMB | DDB1 3336/4885CRBN 2/4885BRD4 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.