Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10334149 | 0.86 | KDM4E (0.75) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL9832407 | 0.84 | KDM4E (0.81) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL8310274 | 0.84 | KDM4E (0.49) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL16884170 | 0.83 | POLB (0.82) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL2092284 | 0.82 | KMT2A (0.54) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL25834338 | 0.81 | KDM4E (0.69) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL8310001 | 0.80 | KDM4E (0.67) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL1889066 | 0.80 | KDM4E (0.67) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL16884075 | 0.80 | KDM4E (0.67) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL11179651 | 0.79 | USP2 (0.69) | KDM4EMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4388312-A | HYPOTENSIVE AGENTS, ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-06-14 | — | — | US | claimed |
| EP-0025692-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1982-12-01 | — | — | EP | claimed |
| EP-0025692-A1 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-03-25 | — | — | EP | claimed |
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-4698340-A | TREATMENT OF CEREBROVASCULAR DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0169712-A2 | New pyrimidine derivatives, processes for preparation thereof and composition containing the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-29 | — | — | EP | disclosed |
| US-4533554-A | ANALGESICS, HYPOTENSIVE AGENTS, ANTI-INFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-08-06 | — | — | US | disclosed |
| US-4388312-A | HYPOTENSIVE AGENTS, ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-06-14 | — | — | US | disclosed |
| EP-0025692-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1982-12-01 | — | — | EP | disclosed |
| EP-0025692-A1 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-03-25 | — | — | EP | disclosed |