Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4811662 | 0.98 | KDM4E (0.65) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL9620879 | 0.98 | KDM4E (0.65) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL9620928 | 0.93 | KDM4E (0.64) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Isopropyl Alcohol SCHEMBL9781878 | 0.93 | KDM4E (0.58) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Isopropyl Alcohol SCHEMBL10448138 | 0.91 | KDM4E (0.57) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL15302757 | 0.86 | KDM4E (0.51) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL10334149 | 0.86 | KDM4E (0.75) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL9212536 | 0.85 | GAA (0.71) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL9832407 | 0.84 | KDM4E (0.81) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL7297538 | 0.84 | SLC6A4 (0.49) | KDM4EMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201268-A2 | Combinations of D4 dopamine receptor antagonists with acetylcholine esterase inhibitors | Pfizer Products Inc. (US) | 2002-05-02 | — | — | EP | claimed |
| JP-61251676-A | — | — | None | — | — | JP | disclosed |
| US-20230365546-A1 | 5-SUBSTITUTED INDOLE 3-AMIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | ORIGIANT PHARMACEUTICAL CO., LTD (CN) | 2023-11-16 | — | — | US | disclosed |
| CN-116637093-A | Application of 2,3, 4-trimethoxybenzaldehyde in preparing medicine for treating symptoms caused by myocardial and/or cerebral ischemia and hypoxia | 郭萍 | 2023-08-25 | — | — | CN | disclosed |
| EP-4212525-A1 | 5-SUBSTITUTED INDOLE 3-AMIDE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | Origiant Pharmaceutical Co., Ltd (CN) | 2023-07-19 | — | — | EP | disclosed |
| US-20180360824-A1 | PROCASPASE-ACTIVATING COMPOUNDS AND METHODS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-12-20 | — | — | US | disclosed |
| US-10022371-B2 | Procaspase-activating compounds and methods | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-07-17 | — | — | US | disclosed |
| US-10022371-B2 | Procaspase-activating compounds and methods | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-07-17 | — | — | US | disclosed |
| US-20150231132-A1 | PROCASPASE-ACTIVATING COMPOUNDS AND METHODS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-08-20 | — | — | US | disclosed |
| US-20150231132-A1 | PROCASPASE-ACTIVATING COMPOUNDS AND METHODS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-08-20 | — | — | US | disclosed |
| EP-0284359-A1 | 1,4-Disubstituted piperazine compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |
| US-4728650-A | ANTIULCER, ANTITUSSIVE, EXPECTORANTS | KURARAY CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |
| EP-0202580-A2 | 3,4-Dihydrobenzopyran derivatives | KURARAY CO., LTD. (JP) | 1986-11-26 | — | — | EP | disclosed |
| JP-S61251676-A | NOVEL TRIMETHOXYBENZYLPIPERAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUND AS ACTIVE COMPONENT | KANEBO LTD | 1986-11-08 | — | — | JP | disclosed |
| EP-0038160-B1 | QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-09-19 | — | — | EP | disclosed |
| US-4393075-A | SLOW-REACTING-SUBSTANCE OF ANAPHYLAXIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-07-12 | — | — | US | disclosed |
| US-4374990-A | ANTIDEPRESSANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-22 | — | — | US | disclosed |
| EP-0038160-A1 | Quinone compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-10-21 | — | — | EP | disclosed |
| US-4115569-A | PARASITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-09-19 | — | — | US | disclosed |
| US-3957790-A | VASODILATORS | TOKYO TANABE COMPANY, LTD. (JA) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365546-A1 | 5-SUBSTITUTED INDOLE 3-AMIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | RIPK1, RIPK3, RIPK2 | KDM4E 1715/4885MEN1 1745/4885KMT2A 2607/4885 |
| US-20150231132-A1 | PROCASPASE-ACTIVATING COMPOUNDS AND METHODS | CASP3, CASP5, CASP6 | KDM4E 1115/4885MEN1 3281/4885KMT2A 3185/4885 |
| US-20180360824-A1 | PROCASPASE-ACTIVATING COMPOUNDS AND METHODS | CASP3, CASP5, CASP6 | KDM4E 1115/4885MEN1 3281/4885KMT2A 3185/4885 |
| US-10022371-B2 | Procaspase-activating compounds and methods | CASP3, CASP5, CASP6 | KDM4E 1115/4885MEN1 3281/4885KMT2A 3185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.