Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9774981 | 0.76 | LMNA (0.32) | P2RX7LMNARAPGEF4IDO1 | |
| SCHEMBL7905835 | 0.75 | TP53 (0.35) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL7894304 | 0.73 | TP53 (0.34) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL2210002 | 0.72 | IDO1 (0.33) | LMNAIDO1 | |
| SCHEMBL25787065 | 0.71 | NOTUM (0.33) | RAPGEF4 | |
| SCHEMBL13990809 | 0.70 | LMNA (0.36) | LMNARAPGEF4IDO1 | |
| SCHEMBL29344193 | 0.70 | PDE2A (0.31) | — | |
| SCHEMBL2211113 | 0.70 | IDO1 (0.32) | IDO1 | |
| SCHEMBL22155162 | 0.70 | IDO1 (0.39) | LMNAIDO1 | |
| SCHEMBL9723067 | 0.69 | RAPGEF4 (0.33) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |