Bromide

Bromide

SCHEMBL2583511

CCCC[N+](CC)(CC)CCCC.[Br-]

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 3/20 0.69
DNM1 Q05193 5/20 0.68
TSHR P16473 2/20 0.61
ALDH1A1 P00352 1/20 0.61
TP53 P04637 1/20 0.61
CYP3A4 P08684 1/20 0.61
ALOX15 P16050 1/20 0.61
ALOX12 P18054 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
HIF1A Q16665 1/20 0.61
HSD17B10 Q99714 1/20 0.61
SLC22A2 O15244 1/20 0.59
NFKB1 P19838 1/20 0.44
KCNA1 Q09470 1/20 0.44
HSP90AA1 P07900 1/20 0.43
RAD52 P43351 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28793843 0.97 SLC22A1 (0.73) SLC22A1DNM1TSHRALDH1A1TP53
SCHEMBL3876642 0.97 SLC22A1 (0.73) SLC22A1DNM1TSHRALDH1A1TP53
Bromide SCHEMBL622840 0.93 DNM1 (0.78) SLC22A1DNM1TSHRALDH1A1TP53
SCHEMBL7638959 0.93 SLC22A1 (0.69) SLC22A1DNM1TSHRALDH1A1TP53
Water SCHEMBL3304283 0.93 SLC22A1 (0.69) SLC22A1DNM1TSHRALDH1A1TP53
SCHEMBL7553616 0.93 SLC22A1 (0.69) SLC22A1DNM1TSHRALDH1A1TP53
Bromide SCHEMBL3680180 0.93 SLC22A1 (0.69) SLC22A1DNM1TSHRALDH1A1TP53
SCHEMBL7553619 0.93 SLC22A1 (0.69) SLC22A1DNM1TSHRALDH1A1TP53
Iodide SCHEMBL5086874 0.93 SLC22A1 (0.69) SLC22A1DNM1TSHRALDH1A1TP53
SCHEMBL27846084 0.93 SLC22A1 (0.69) SLC22A1DNM1TSHRALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101396690-B Multilayer coating film-forming method KANSAI PAINT CO LTD 2013-08-21 CN claimed
US-4522729-A CXONTACTING IMPORITIES WITH TETRAALKYLAMMONIUM SALT PHILLIPS PETROLEUM COMPANY (US) 1985-06-11 US claimed
WO-2024190910-A1 ONE-COMPONENT CURABLE COATING COMPOSITION 関西ペイント株式会社 2024-09-19 WO disclosed
CN-101396690-B Multilayer coating film-forming method KANSAI PAINT CO LTD 2013-08-21 CN disclosed
CN-101293238-B Multilayer coating film- forming method KANSAI PAINT CO LTD 2013-05-01 CN disclosed
US-8048491-B2 2-coat-1-bake system; an acrylic-type acid and/or acrylic-type anhydride, an epoxy-functional acrylic resin, and a glycol ether solvent; improved workability, electrostatic coatability, and gloss; clear coat paints KANSAI PAINT CO., LTD. (JP) 2011-11-01 US disclosed
US-20090087667-A1 Multilayer coating film-forming method KANSAI PAINT CO., LTD. 2009-04-02 US disclosed
CN-101396690-A Multilayer coating film-forming method KANSAI PAINT CO LTD (JP) 2009-04-01 CN disclosed
US-20080268256-A1 Multilayer coating film- forming method KANSAI PAINT CO., LTD. 2008-10-30 US disclosed
CN-101293238-A Multilayer coating film- forming method KANSAI PAINT CO LTD (JP) 2008-10-29 CN disclosed
US-20080214386-A1 Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-09-04 US disclosed
EP-0161550-B1 PROCESS FOR PRODUCING AN ALIPHATIC ISOCYANATE Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1988-01-20 EP disclosed
US-4587056-A CARBONYLATION, OXIDATION, CATALYST ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1986-05-06 US disclosed
EP-0161550-A1 Process for producing an aliphatic isocyanate Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-11-21 EP disclosed
US-4522729-A CXONTACTING IMPORITIES WITH TETRAALKYLAMMONIUM SALT PHILLIPS PETROLEUM COMPANY (US) 1985-06-11 US disclosed