Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.69 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346989 | 0.97 | SLC22A1 (0.73) | SLC22A1DNM1TSHRALDH1A1TP53 | |
| Water SCHEMBL1332993 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1TSHRALDH1A1TP53 | |
| SCHEMBL10598482 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1TSHRALDH1A1TP53 | |
| Iodide SCHEMBL4333792 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1TSHRALDH1A1TP53 | |
| Bromide SCHEMBL2583511 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1TSHRALDH1A1TP53 | |
| SCHEMBL10598485 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1TSHRALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL5084823 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1TSHRALDH1A1TP53 | |
| Bromide SCHEMBL622840 | 0.93 | DNM1 (0.78) | SLC22A1DNM1TSHRALDH1A1TP53 | |
| Bromide SCHEMBL10697230 | 0.90 | DNM1 (0.83) | SLC22A1DNM1TSHRALDH1A1TP53 | |
| SCHEMBL11806867 | 0.90 | DNM1 (0.78) | SLC22A1DNM1TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159094-A2 | PROCESS OF MAKING 3α-HYDROXY-3β-METHOXYMETHYL-21-(1'- IMIDAZOLYL)-5α-PREGNAN-20-ONE | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-08-24 | — | — | WO | claimed |
| CN-102309945-A | Multi-component surfactant and preparation method thereof | SHENZHEN MCT TECHNOLOGY CO LTD | 2012-01-11 | — | — | CN | claimed |
| US-20060281926-A1 | Synthesis of 2-alkylcysteine via phase transfer catalysis | GIMI RAYOMAND H | 2006-12-14 | — | — | US | claimed |
| US-4065601-A | Two phase electrolytes used as halogen traps in metal halogen secondary cells and batteries | ECO-CONTROL, INC. (US) | 1977-12-27 | — | — | US | claimed |
| JP-55066531-A | — | — | None | — | — | JP | disclosed |
| WO-2024004508-A1 | METHOD FOR PRODUCING POLYSACCHARIDE FIBER | 旭化成株式会社 | 2024-01-04 | — | — | WO | disclosed |
| WO-2023159094-A2 | PROCESS OF MAKING 3α-HYDROXY-3β-METHOXYMETHYL-21-(1'- IMIDAZOLYL)-5α-PREGNAN-20-ONE | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-08-24 | — | — | WO | disclosed |
| EP-1682609-B1 | METHOD OF MODIFYING A FLUOROPOLYMER AND ARTICLES THEREBY | 3M INNOVATIVE PROPERTIES CO (US) | 2015-03-11 | — | — | EP | disclosed |
| CN-102309945-B | Multi-component surfactant and preparation method thereof | SHENZHEN MCT TECHNOLOGY CO LTD | 2012-12-19 | — | — | CN | disclosed |
| CN-102309945-A | Multi-component surfactant and preparation method thereof | SHENZHEN MCT TECHNOLOGY CO LTD | 2012-01-11 | — | — | CN | disclosed |
| EP-1814837-B1 | A METHOD FOR PRODUCING 4,4,4-TRIFLUOROBUTANE-2-ONE | CENTRAL GLASS CO LTD (JP) | 2010-02-24 | — | — | EP | disclosed |
| EP-2014703-B1 | Process of preparing a composite article | 3M INNOVATIVE PROPERTIES CO (US) | 2009-12-09 | — | — | EP | disclosed |
| EP-0268261-A1 | Process for producing 1-hydrocarbyl mercaptans | PHILLIPS PETROLEUM COMPANY (US) | 1988-05-25 | — | — | EP | disclosed |
| EP-0004606-B1 | PROCESS FOR PREPARING ANILINE COMPOUNDS | ETHYL CORPORATION (US) | 1982-03-10 | — | — | EP | disclosed |
| US-4267317-A | CONCURRENT ETHERIFICATION AND DEHYDROGENATION OF A PHENOL BY REACTING WITH A 1-CARBOXY-3-HALOALKANE USING AN ALKALI METAL COMPOUND AND A SPECIAL SOLVENT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-05-12 | — | — | US | disclosed |
| US-4254262-A | IN THE PRESENCE OF A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |
| JP-S5566531-A | PREPARATION OF PHENOXYALKENE DERIVATIVE | IHARA CHEM IND CO LTD | 1980-05-20 | — | — | JP | disclosed |
| US-4186147-A | DISPLACEMENT OF THIOCYANOANILINE WITH AN ALCOHOL TO FORM THIOALKYL ANILINE | ETHYL CORPORATION (US) | 1980-01-29 | — | — | US | disclosed |
| EP-0004606-A2 | Process for preparing aniline compounds | ETHYL CORPORATION (US) | 1979-10-17 | — | — | EP | disclosed |
| US-4022816-A | TRIALKYL AMMONIUM OR PHOSPHONIUM CATALYST | ETHYL CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281926-A1 | Synthesis of 2-alkylcysteine via phase transfer catalysis | DIMT1, ICMT, CNDP2 | SLC22A1 1163/4885DNM1 1352/4885TSHR 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.