Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 6/20 | 0.48 |
| ▸ | MMP9 | P14780 | 6/20 | 0.48 |
| ▸ | MMP13 | P45452 | 6/20 | 0.48 |
| ▸ | MMP8 | P22894 | 4/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 6/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25835159 | 0.92 | ERCC1 (0.57) | ERCC1DNASE1FEN1ERCC4MMP2 | |
| SCHEMBL25834657 | 0.77 | MAPK8 (0.52) | MAPK10MAPK14KDM4EMEN1CYP1A2 | |
| SCHEMBL30539515 | 0.77 | MAPK10 (0.49) | MAPK10MAPK14KDM4EMEN1CYP1A2 | |
| SCHEMBL17742373 | 0.77 | MAPK10 (0.49) | MAPK10MAPK14KDM4EMEN1CYP1A2 | |
| SCHEMBL21636104 | 0.76 | PARP1 (0.63) | FEN1MMP2MMP9MMP13MMP8 | |
| SCHEMBL17794530 | 0.73 | ALDH1A1 (0.46) | ERCC1DNASE1FEN1ERCC4MAPK10 | |
| SCHEMBL24406180 | 0.73 | AHR (0.55) | ERCC1DNASE1FEN1ERCC4MMP2 | |
| SCHEMBL20227588 | 0.73 | PARP1 (0.57) | FEN1KDM4EMEN1CYP1A2KMT2A | |
| SCHEMBL7072330 | 0.73 | BRAF (0.58) | ERCC1DNASE1FEN1ERCC4MAPK10 | |
| SCHEMBL6526939 | 0.72 | AURKA (0.67) | ERCC1DNASE1FEN1ERCC4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110742-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |