Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 5/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CASP9 | P55211 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 5/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25834660 | 0.94 | MAPK8 (0.52) | MAPK8MAPK10MAPK14APAF1TDP2 | |
| SCHEMBL25834665 | 0.86 | BRD4 (0.55) | MAPK8MAPK10MAPK14APAF1TDP2 | |
| SCHEMBL18253544 | 0.82 | MAPK8 (0.57) | MAPK8MAPK10MAPK14APAF1TDP2 | |
| SCHEMBL25835159 | 0.81 | ERCC1 (0.57) | MAPK10MAPK14APAF1TDP2CDC25B | |
| SCHEMBL25834655 | 0.79 | APAF1 (0.50) | MAPK8MAPK10MAPK14APAF1TDP2 | |
| SCHEMBL21168871 | 0.79 | MAPK8 (0.56) | MAPK8MAPK10MAPK14APAF1TDP2 | |
| SCHEMBL25835280 | 0.77 | ERCC1 (0.50) | MAPK10MAPK14PARP1BRD4ALDH1A1 | |
| SCHEMBL20031187 | 0.76 | KIF11 (0.53) | MAPK8MAPK10MAPK14APAF1TDP2 | |
| SCHEMBL16925710 | 0.72 | C1R (0.48) | MAPK8MAPK10MAPK14APAF1TDP2 | |
| SCHEMBL21577615 | 0.72 | MAPK14 (0.49) | MAPK8MAPK10MAPK14APAF1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110742-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |