Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 8/20 | 0.40 |
| ▸ | PYGB | P11216 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.35 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21137910 | 0.93 | TLR4 (0.44) | TLR4PYGBMAPK1LY96 | |
| SCHEMBL31353005 | 0.93 | TLR4 (0.44) | TLR4PYGBMAPK1LY96 | |
| SCHEMBL21058358 | 0.91 | TLR4 (0.42) | TLR4PYGBPTGS1PTGS2SLC2A1 | |
| SCHEMBL21137953 | 0.89 | PYGB (0.45) | TLR4PYGBPTGS1PTGS2MAPK1 | |
| SCHEMBL21138039 | 0.89 | PYGB (0.45) | TLR4PYGBPTGS1PTGS2MAPK1 | |
| SCHEMBL21137960 | 0.87 | PYGB (0.40) | TLR4PYGBPTGS1PTGS2SLC2A1 | |
| SCHEMBL21137917 | 0.87 | PYGB (0.40) | TLR4PYGBPTGS1PTGS2MAPK1 | |
| Hydrochloric Acid SCHEMBL21058362 | 0.86 | PYGB (0.39) | TLR4PYGBPTGS1PTGS2SLC2A1 | |
| SCHEMBL21138675 | 0.86 | PYGB (0.39) | TLR4PYGBPTGS1PTGS2MAPK1 | |
| SCHEMBL21138044 | 0.86 | PYGB (0.48) | TLR4PYGBPTGS1PTGS2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718636-B2 | Glucosamine derivatives for the prevention or treatment of joint disorders | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-08-08 | — | — | US | disclosed |
| US-20230227488-A1 | GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | RISEN SUZHOU PHARMA TECH CO LTD (CN) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718636-B2 | Glucosamine derivatives for the prevention or treatment of joint disorders | OGT, UGGT1, GLA | TLR4 660/4885PYGB 760/4885PTGS1 271/4885 |
| US-20230227488-A1 | GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | OGT, UGGT1, GLA | TLR4 896/4885PYGB 601/4885PTGS1 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.