Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.67 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.67 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.63 |
| ▸ | CNR1 | P21554 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29255797 | 0.91 | LPAR1 (0.56) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL4387701 | 0.90 | CNR1 (0.68) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL4397932 | 0.89 | CNR1 (0.67) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL4384307 | 0.89 | EPHX2 (0.72) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL29360245 | 0.89 | CNR1 (0.67) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL24022038 | 0.89 | CNR1 (0.67) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL4392061 | 0.89 | SLC6A5 (0.71) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL4384309 | 0.89 | EPHX2 (0.72) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL4397935 | 0.89 | CNR1 (0.67) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL10028552 | 0.88 | SLC6A5 (0.69) | LPAR1LPAR2ENPP2EPHX2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226193-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | Arrowhead Pharmaceuticals, Inc. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226193-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | CPT1B, MUSK, MYLK2 | LPAR1 147/4885LPAR2 74/4885ENPP2 658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.