SCHEMBL25835717

SCHEMBL25835717

C#CCOCCC(=O)N[C@@H](CCC(=O)NCCOCCC(=O)NCCOCCNC(=O)CCCCCCCCCCCCCCC)C(=O)NCCOCCC(=O)NCCOCCNC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.61
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ LPAR3 Q9UBY5 4/20 0.45
▸ NOD1 Q9Y239 5/20 0.44
▸ LPAR1 Q92633 2/20 0.44
▸ TLR2 O60603 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22923670 0.82 GLP1R (0.73) GLP1RLPAR3NOD1LPAR1TLR2
SCHEMBL25835728 0.82 GLP1R (0.59) GLP1RLPAR3NOD1LPAR1TLR2
SCHEMBL4828756 0.80 GLP1R (0.64) GLP1RLPAR3NOD1LPAR1
SCHEMBL13336948 0.80 GLP1R (0.64) GLP1RLPAR3NOD1LPAR1
SCHEMBL12588574 0.80 GLP1R (0.64) GLP1RLPAR3NOD1LPAR1
SCHEMBL14735663 0.80 GLP1R (0.67) GLP1RNOD1
SCHEMBL14735664 0.80 GLP1R (0.67) GLP1RNOD1
SCHEMBL26257845 0.80 GLP1R (0.64) GLP1RLPAR3NOD1LPAR1TLR2
SCHEMBL18354362 0.79 GLP1R (0.70) GLP1RLPAR3NOD1LPAR1TLR2
SCHEMBL14240494 0.79 GLP1R (0.70) GLP1RLPAR3NOD1LPAR1TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 GLP1R 1985/4885L3MBTL1 1095/4885LPAR3 153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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