SCHEMBL25835894

SCHEMBL25835894

CCCNC(=O)CCOCCNC(=O)CCOCCNC(=O)CCOCCN(CCOCCC(=O)NCCOCCC(=O)NCCOCCC(=O)NCCC)C(=O)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 3/20 0.42
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
HDAC3 O15379 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
NCOR2 Q9Y618 1/20 0.34
DNM1 Q05193 2/20 0.33
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA7 P43166 1/20 0.31
CA2 P00918 1/20 0.31
CNR1 P21554 2/20 0.31
CASP2 P42575 1/20 0.30
MCL1 Q07820 1/20 0.30
PLK1 P53350 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26033149 0.99 CA14 (0.41) CA14GAAKMT2AHDAC3HDAC1
SCHEMBL25703082 0.81 TDP1 (0.43) GAAKMT2ACA12CA1CA2
SCHEMBL14706731 0.78 CA14 (0.43) CA14HDAC3HDAC1HDAC2NCOR2
SCHEMBL23191212 0.77 DNM1 (0.41) GAAKMT2ADNM1CNR1CASP2
SCHEMBL25835271 0.76 TDP1 (0.44) GAAKMT2ACA12CA1CA2
SCHEMBL16206190 0.76 CA14 (0.44) CA14GAAKMT2ACA12CA1
SCHEMBL25835897 0.75 CA14 (0.41) CA14HDAC3HDAC1HDAC2NCOR2
SCHEMBL25933067 0.75 TLR2 (0.39) CA14KMT2ACA12CA1CA2
SCHEMBL25031587 0.75 CA14 (0.40) CA14HDAC3HDAC1HDAC2NCOR2
SCHEMBL25933059 0.75 TLR2 (0.39) CA14KMT2ACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 CA14 4660/4885GAA 201/4885KMT2A 1603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.