SCHEMBL25836123

SCHEMBL25836123

O=c1[nH]c2cc3c(cc2c2c1ccc1[nH]c4ccccc4c12)[nH]c1ccccc13

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.56
PARP1 P09874 10/20 0.53
ALDH1A1 P00352 3/20 0.53
KDM4E B2RXH2 3/20 0.53
TNKS O95271 2/20 0.53
TNKS2 Q9H2K2 2/20 0.53
GPR3 P46089 2/20 0.53
HSD17B10 Q99714 2/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
LMNA P02545 1/20 0.53
CYP1A2 P05177 1/20 0.53
BLM P54132 1/20 0.53
PMP22 Q01453 1/20 0.53
PARP15 Q460N3 1/20 0.53
GABRP O00591 1/20 0.51
GABRD O14764 1/20 0.51
GABRA1 P14867 1/20 0.51
GABRB1 P18505 1/20 0.51
GABRG2 P18507 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25836015 0.95 PARP1 (0.51) AHRPARP1ALDH1A1KDM4ETNKS
SCHEMBL13466220 0.87 AHR (0.75) AHRALDH1A1KDM4EGPR3HSD17B10
SCHEMBL25867963 0.85 PARP1 (0.57) AHRPARP1ALDH1A1KDM4ETNKS
SCHEMBL25836500 0.85 PARP1 (0.57) PARP1ALDH1A1KDM4ETNKSTNKS2
SCHEMBL25836016 0.84 AHR (0.52) AHRPARP1ALDH1A1KDM4ETNKS
SCHEMBL14314921 0.83 AHR (0.67) AHRPARP1ALDH1A1KDM4EGPR3
SCHEMBL23132411 0.82 PARP1 (0.57) PARP1ALDH1A1KDM4ETNKSTNKS2
SCHEMBL12219440 0.81 AHR (0.72) AHRALDH1A1KDM4EGPR3HSD17B10
SCHEMBL25836125 0.81 GABRP (0.65) AHRPARP1ALDH1A1KDM4ETNKS
SCHEMBL25835163 0.81 GABRP (0.64) PARP1ALDH1A1KDM4ETNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023110742-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-22 WO disclosed