SCHEMBL25836500

SCHEMBL25836500

O=c1[nH]c2ccc3[nH]c4ccccc4c3c2c2c1ccc1[nH]c3ccccc3c12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 9/20 0.57
KDM4E B2RXH2 5/20 0.57
ALDH1A1 P00352 4/20 0.57
LMNA P02545 2/20 0.57
TNKS O95271 2/20 0.57
TNKS2 Q9H2K2 2/20 0.57
GPR3 P46089 2/20 0.57
HSD17B10 Q99714 2/20 0.57
MEN1 O00255 1/20 0.57
CYP1A2 P05177 1/20 0.57
BLM P54132 1/20 0.57
PMP22 Q01453 1/20 0.57
KMT2A Q03164 1/20 0.57
PARP15 Q460N3 1/20 0.57
GABRP O00591 1/20 0.55
GABRD O14764 1/20 0.55
GABRA1 P14867 1/20 0.55
GABRB1 P18505 1/20 0.55
GABRG2 P18507 1/20 0.55
GABRB3 P28472 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23132411 0.89 PARP1 (0.57) PARP1KDM4EALDH1A1LMNATNKS
SCHEMBL23132415 0.87 PARP1 (0.64) PARP1KDM4EALDH1A1LMNATNKS
SCHEMBL25867963 0.85 PARP1 (0.57) PARP1KDM4EALDH1A1LMNATNKS
SCHEMBL25836123 0.85 AHR (0.56) PARP1KDM4EALDH1A1LMNATNKS
SCHEMBL25835163 0.84 GABRP (0.64) PARP1KDM4EALDH1A1LMNATNKS
SCHEMBL25836015 0.84 PARP1 (0.51) PARP1KDM4EALDH1A1LMNATNKS
SCHEMBL8926269 0.82 PARP1 (0.60) PARP1KDM4EALDH1A1LMNATNKS
SCHEMBL1635466 0.82 ALDH1A1 (0.68) PARP1KDM4EALDH1A1LMNAGPR3
SCHEMBL29380761 0.82 ALDH1A1 (0.68) PARP1KDM4EALDH1A1LMNAGPR3
SCHEMBL25836125 0.82 GABRP (0.65) PARP1KDM4EALDH1A1LMNATNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023110742-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-22 WO disclosed