Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.48 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21889851 | 0.81 | AOC3 (0.61) | AOC3NPC1RAB9AL3MBTL1PKM | |
| SCHEMBL23590407 | 0.80 | NPC1 (0.51) | AOC3NPC1RAB9AL3MBTL1PKM | |
| SCHEMBL22095234 | 0.76 | SIGMAR1 (0.72) | TMEM97SIGMAR1 | |
| SCHEMBL21914584 | 0.75 | NPC1 (0.44) | AOC3NPC1RAB9AL3MBTL1PKM | |
| SCHEMBL31566316 | 0.74 | MMP13 (0.59) | NPC1RAB9AL3MBTL1PKMSMN1; SMN2 | |
| SCHEMBL22165963 | 0.74 | ENPP3 (0.51) | NPC1RAB9AL3MBTL1PKMSMN1; SMN2 | |
| SCHEMBL1055899 | 0.74 | MAPT (0.53) | NPC1RAB9AL3MBTL1PKMSMN1; SMN2 | |
| SCHEMBL25836249 | 0.74 | IKBKE (0.50) | NPC1RAB9AL3MBTL1ENPP3ENPP1 | |
| SCHEMBL21914567 | 0.74 | AOC3 (0.50) | AOC3NPC1RAB9AKMT2ASIGMAR1 | |
| SCHEMBL12989241 | 0.73 | ENPP3 (0.53) | NPC1RAB9AL3MBTL1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626699-B1 | SSAO INHIBITOR | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2023-07-12 | — | — | EP | disclosed |