SCHEMBL258366

SCHEMBL258366

Nc1ccc(O)cc1C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.65
KDM4E B2RXH2 4/20 0.65
GFER P55789 1/20 0.65
RXFP1 Q9HBX9 1/20 0.65
MAPT P10636 4/20 0.63
MEN1 O00255 4/20 0.63
TDP1 Q9NUW8 3/20 0.63
THRB P10828 2/20 0.63
RECQL P46063 2/20 0.63
USP2 O75604 2/20 0.63
POLB P06746 2/20 0.63
MCL1 Q07820 2/20 0.63
PKM P14618 1/20 0.63
APEX1 P27695 1/20 0.63
BLM P54132 1/20 0.63
CA12 O43570 2/20 0.61
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30120212 1.00 KMT2A (0.65) KMT2AKDM4EGFERRXFP1MAPT
Hydrochloric Acid SCHEMBL27577526 0.98 KMT2A (0.67) KMT2AKDM4EGFERRXFP1MAPT
SCHEMBL8220007 0.89 KDM4E (0.55) KMT2AKDM4EGFERRXFP1MAPT
Alcohol SCHEMBL28066280 0.89 KMT2A (0.56) KMT2AKDM4EGFERRXFP1MAPT
SCHEMBL562543 0.82 IKBKB (0.55) KMT2AKDM4EGFERRXFP1MAPT
SCHEMBL20853600 0.82 CA12 (0.45) KMT2AKDM4EGFERRXFP1MAPT
SCHEMBL440293 0.82 ALDH1A1 (0.61) KMT2AKDM4EGFERRXFP1MAPT
SCHEMBL11840032 0.80 ALDH1A1 (0.46) KMT2AKDM4EGFERRXFP1MAPT
Hydrochloric Acid SCHEMBL9797011 0.80 ALDH1A1 (0.59) KMT2AKDM4EGFERRXFP1MAPT
SCHEMBL9851201 0.79 MAPT (0.66) KMT2AMAPTMEN1USP2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120195409-A Composition for diagnosing sepsis and medicament for sepsis preventive treatment 北京大学第三医院(北京大学第三临床医学院) 2025-06-24 CN claimed
US-20250154095-A1 SYNTHESIS METHOD OF AVENANTHRAMIDE C DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY-ACADEMY COOPERATION (KR) 2025-05-15 US claimed
CN-119529929-A Lubricating oil composition for improving friction characteristics of gears and preparation method thereof 中国石油天然气股份有限公司 2025-02-28 CN claimed
CN-119529210-A Ashless dispersant, and preparation method and application thereof 中国石油天然气股份有限公司 2025-02-28 CN claimed
CN-118566488-A Reagent combination for detecting depression, manufacturing method, detection system and application thereof 合肥歆智医疗器械有限公司 2024-08-30 CN claimed
CN-116377715-B High-elasticity ultraviolet-resistant fabric and preparation method thereof 盐城市金达纺织有限公司 2024-08-27 CN claimed
CN-118294676-A Depression detection reagent based on key marker, detection system and application thereof 合肥歆智医疗器械有限公司 2024-07-05 CN claimed
CN-118230955-A Model training method for depression detection, detection system, program, and storage medium 合肥歆智医疗器械有限公司 2024-06-21 CN claimed
CN-118226045-A Detection method, reagent and detection system for simultaneously detecting more than ten markers 合肥歆智医疗器械有限公司 2024-06-21 CN claimed
CN-118126051-A Polymorphic substance of mutant BRAF degradation agent and preparation method thereof C4医药公司 2024-06-04 CN claimed
EP-0648488-B1 Method to alter hairgrowth and compositions therefor OREAL (FR) 2000-11-29 EP claimed
WO-2000059875-A2 NOVEL INHIBITORS OF FORMATION OF ADVANCED GLYCATION ENDPRODUCTS (AGE'S) CITY OF HOPE (US) 2000-10-12 WO claimed
US-5928654-A Modulating body/cranial hair growth with lipoxygenase/cyclooxygenase inhibitors SOCIETE L'OREAL S.A. (FR) 1999-07-27 US claimed
US-5919846-A COLORFASTNESS; WATERPROOFING MILLIKEN RESEARCH CORPORATION (US) 1999-07-06 US claimed
EP-0474874-B1 Maillard Reaction inhibitor compositions SENJU PHARMA CO (JP) 1995-10-18 EP claimed
EP-0455168-B1 DYEING COMPOSITION FOR KERATIN FIBER Kao Corporation (JP) 1993-09-22 EP claimed
EP-0474874-A1 Maillard Reaction inhibitor compositions Senju Pharmaceutical Co., Ltd. (JP) 1992-03-18 EP claimed
US-5089026-A 1,5-Dihydroxynaphthalene, 2-amino-5-hydroxybenzoic acid, cosmetically acceptable base KAO CORPORATION (JP) 1992-02-18 US claimed
EP-0455168-A1 Dyeing composition for keratin fiber Kao Corporation (JP) 1991-11-06 EP claimed
US-4314078-A Process for preparing 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitro-N-alkanesulphonyl benzamides from a benzoic acid derivative and intermediates ICI AMERICAS INC. (US) 1982-02-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154095-A1 SYNTHESIS METHOD OF AVENANTHRAMIDE C OAT, MCCC2, OTC KMT2A 399/4885KDM4E 1289/4885GFER 1085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.