SCHEMBL25837121

SCHEMBL25837121

CN(CC(=O)NCCCNC(=O)C1(C)CC1)CC(=O)NCCCNC(=O)C1(C)CC1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
DRD2 P14416 2/20 0.34
DRD4 P21917 2/20 0.34
RAB9A P51151 1/20 0.33
SPHK1 Q9NYA1 6/20 0.32
DNM1 Q05193 1/20 0.32
HDAC1 Q13547 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25817012 0.97 SMN1; SMN2 (0.42) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25817163 0.93 MEN1 (0.35) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25817016 0.89 DNM1 (0.50) DNM1
SCHEMBL25816682 0.79 HPGD (0.44) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25817168 0.78 HPGD (0.47) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25816839 0.78 HPGD (0.43) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25817185 0.77 CYP3A4 (0.37) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL23133081 0.74 SPHK1 (0.47) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25817013 0.74 MEN1 (0.64) SMN1; SMN2MEN1KMT2ADNM1
SCHEMBL3427647 0.73 SPHK1 (0.54) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125806-A1 CONJUGATE FOR PREVENTING AND TREATING VIRAL INFECTIONS AND USE THEREOF 苏州爱科百发生物医药技术有限公司 2023-07-06 WO disclosed