SCHEMBL25817185

SCHEMBL25817185

CN(CCNC(=O)C1(C)CC1)CCNC(=O)C1(C)CC1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
HPGD P15428 2/20 0.36
LMNA P02545 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
FFAR3 O14843 1/20 0.34
PRMT1 Q99873 1/20 0.34
DRD2 P14416 2/20 0.34
DRD4 P21917 2/20 0.34
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
RORC P51449 1/20 0.32
FDPS P14324 1/20 0.32
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
POLB P06746 2/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25816682 0.87 HPGD (0.44) CYP3A4CYP2C19SMN1; SMN2HPGDLMNA
SCHEMBL25816839 0.85 HPGD (0.43) CYP3A4CYP2C19SMN1; SMN2HPGDLMNA
SCHEMBL25817168 0.85 HPGD (0.47) CYP3A4CYP2C19SMN1; SMN2HPGDLMNA
SCHEMBL25816575 0.83 CHRM2 (0.42) CYP3A4CYP2C19SMN1; SMN2MEN1KMT2A
SCHEMBL25817180 0.80 ACHE (0.39) CYP3A4CYP2C19SMN1; SMN2HPGDLMNA
SCHEMBL25837186 0.80 CYP3A4 (0.37) CYP3A4CYP2C19SMN1; SMN2HPGDLMNA
SCHEMBL25817163 0.79 MEN1 (0.35) CYP3A4CYP2C19SMN1; SMN2HPGDLMNA
SCHEMBL2055526 0.79 DRD2 (0.43) SMN1; SMN2LMNADRD2DRD4FDPS
SCHEMBL23329478 0.77 POLB (0.47) CYP3A4CYP2C19SMN1; SMN2HPGDLMNA
SCHEMBL25837121 0.77 CYP3A4 (0.43) CYP3A4CYP2C19SMN1; SMN2HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125806-A1 CONJUGATE FOR PREVENTING AND TREATING VIRAL INFECTIONS AND USE THEREOF 苏州爱科百发生物医药技术有限公司 2023-07-06 WO disclosed