SCHEMBL25837162

SCHEMBL25837162

Cc1ccc2c(c1)Cc1cc(OCc3ccccc3)c3cc(C)ccc3c1-2

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PTGER1 P34995 1/20 0.39
PTGER4 P35408 1/20 0.39
PTGER3 P43115 1/20 0.39
PTGER2 P43116 1/20 0.39
MAOB P27338 2/20 0.38
CHRNA7 P36544 2/20 0.36
STAT3 P40763 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
BRD4 O60885 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.35
HRH3 Q9Y5N1 2/20 0.34
MAOA P21397 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25876813 0.79 MAOB (0.44) MAOBCHRNA7
SCHEMBL17736806 0.74 MAPT (0.43) MAPTMAPK1TDP1L3MBTL1PTGER1
SCHEMBL25837150 0.74 MAPT (0.43) MAPTMAPK1TDP1L3MBTL1PTGER1
SCHEMBL17736807 0.73 MAPT (0.42) MAPTMAPK1TDP1L3MBTL1PTGER1
SCHEMBL25837151 0.72 MAPT (0.41) MAPTMAPK1TDP1L3MBTL1PTGER1
SCHEMBL17736791 0.71 PTGER1 (0.44) MAPTMAPK1TDP1L3MBTL1PTGER1
SCHEMBL17736805 0.71 MCL1 (0.47) PTGER1PTGER4PTGER3PTGER2HTT
SCHEMBL1817753 0.70 METAP1 (0.39) MAPTTDP1MAOBSMN1; SMN2MAOA
SCHEMBL17736790 0.70 MAPT (0.46) MAPTMAPK1TDP1L3MBTL1PTGER1
SCHEMBL30461328 0.69 MAPT (0.45) MAPTMAPK1TDP1L3MBTL1PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023136213-A1 PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES 株式会社トクヤマ 2023-07-20 WO disclosed