Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17736807 | 0.96 | MAPT (0.42) | MAPTMAPK1TDP1L3MBTL1MAOB | |
| SCHEMBL25837150 | 0.87 | MAPT (0.43) | MAPTMAPK1TDP1L3MBTL1MAOB | |
| SCHEMBL15763617 | 0.83 | MGAM (0.44) | MAPTL3MBTL1SMN1; SMN2MGAMGAA | |
| SCHEMBL25837551 | 0.82 | GSK3B (0.50) | MAPTMAOBHTTSMN1; SMN2MGAM | |
| SCHEMBL17736783 | 0.82 | FFAR1 (0.43) | MAPTMAPK1TDP1L3MBTL1MAOB | |
| SCHEMBL17736806 | 0.82 | MAPT (0.43) | MAPTMAPK1TDP1L3MBTL1MAOB | |
| SCHEMBL18827134 | 0.81 | GSK3B (0.54) | MAPTMAOBSMN1; SMN2MGAMGAA | |
| SCHEMBL25837233 | 0.79 | CTSV (0.46) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL17736805 | 0.78 | MCL1 (0.47) | PTGER1PTGER4PTGER3PTGER2LRRK2 | |
| SCHEMBL4568722 | 0.77 | MAPT (0.38) | MAPTMAPK1TDP1L3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023140186-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-27 | — | — | WO | disclosed |
| WO-2023136213-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-20 | — | — | WO | disclosed |