Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25837151 | 0.87 | MAPT (0.41) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| SCHEMBL17736806 | 0.84 | MAPT (0.43) | MAPTMAPK1TDP1L3MBTL1CDK1 | |
| SCHEMBL25876903 | 0.83 | GSK3B (0.51) | MAPTGSK3BCDK5CDK5R1HTT | |
| SCHEMBL17736807 | 0.83 | MAPT (0.42) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| SCHEMBL18827135 | 0.82 | GSK3B (0.55) | MAPTGSK3BCDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL17736805 | 0.80 | MCL1 (0.47) | MRGPRX4MCL1PTGER1PTGER4PTGER3 | |
| SCHEMBL25837218 | 0.80 | CTSV (0.46) | MAPTMAPK1TDP1L3MBTL1CDK1 | |
| SCHEMBL25876387 | 0.78 | CDK1 (0.35) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| SCHEMBL22163293 | 0.76 | MAPT (0.53) | MAPTHTTGAAALDH1A1LMNA | |
| SCHEMBL25876739 | 0.76 | GSK3B (0.47) | GSK3BCDK5CDK5R1MAOBAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023136213-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-20 | — | — | WO | disclosed |