Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25837478 | 0.87 | MGAM (0.46) | CTSLCDK5CDK5R1CDK1CCNB1 | |
| SCHEMBL25837414 | 0.87 | PTPN1 (0.44) | CTSVCTSLAPPCDK5CDK5R1 | |
| SCHEMBL25876599 | 0.87 | CDK5 (0.38) | CTSVCTSLAPPCDK5CDK5R1 | |
| SCHEMBL15763617 | 0.87 | MGAM (0.44) | CTSVCTSLAPPCDK5CDK5R1 | |
| SCHEMBL18827134 | 0.86 | GSK3B (0.54) | CTSLAPPCDK5CDK5R1MGAM | |
| SCHEMBL25837218 | 0.85 | CTSV (0.46) | CTSVCTSLCDK5CDK5R1CDK1 | |
| SCHEMBL17736783 | 0.84 | FFAR1 (0.43) | CDK5CDK5R1CDK1CCNB1NPC1 | |
| SCHEMBL4568722 | 0.84 | MAPT (0.38) | APPCDK5CDK5R1CDK1CCNB1 | |
| SCHEMBL15906565 | 0.84 | HTR1A (0.37) | CTSVCTSLAPPCDK5CDK5R1 | |
| SCHEMBL17736807 | 0.83 | MAPT (0.42) | CDK5CDK5R1CDK1CCNB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023136213-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-20 | — | — | WO | disclosed |