SCHEMBL25837259

SCHEMBL25837259

CCCCCN1/C(=C/C=C2\CCC(/C=C/C3=[N+](CCCCS(=O)(=O)[O-])c4ccc(Cl)cc4C3(C)C)=C2N(C)C(=O)OC(C)(C)C)C(C)(C)c2cc(Cl)ccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.44
FOLH1 Q04609 4/20 0.43
PRMT1 Q99873 3/20 0.43
HTR1A P08908 1/20 0.42
PRMT5 O14744 1/20 0.40
CARM1 Q86X55 1/20 0.40
PRMT8 Q9NR22 1/20 0.40
BLM P54132 1/20 0.39
FOLR1 P15328 5/20 0.38
HRH2 P25021 3/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
HRH3 Q9Y5N1 2/20 0.38
MLNR O43193 1/20 0.38
NR1I2 O75469 1/20 0.38
PGR P06401 1/20 0.38
ADRB1 P08588 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
DRD2 P14416 1/20 0.38
ADRA2B P18089 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26683030 0.90 PTPN1 (0.48) PTPN1FOLH1PRMT1HTR1APRMT5
SCHEMBL13100809 0.89 PRMT1 (0.42) PTPN1FOLH1PRMT1HTR1APRMT5
SCHEMBL12414956 0.88 PTPN1 (0.49) PTPN1FOLH1PRMT1HTR1APRMT5
SCHEMBL12414957 0.88 PTPN1 (0.49) PTPN1FOLH1PRMT1HTR1APRMT5
SCHEMBL13100810 0.87 PRMT1 (0.43) PTPN1FOLH1PRMT1HTR1APRMT5
SCHEMBL25862037 0.87 PTPN1 (0.47) PTPN1FOLH1PRMT1HTR1APRMT5
SCHEMBL20173602 0.86 HTR1A (0.52) PTPN1FOLH1PRMT1HTR1ABLM
SCHEMBL13531857 0.85 HTR1A (0.47) PTPN1FOLH1PRMT1HTR1ABLM
SCHEMBL23564919 0.84 PTPN1 (0.53) PTPN1FOLH1PRMT1HTR1APRMT5
SCHEMBL17717975 0.83 MLNR (0.49) PTPN1FOLH1PRMT1PRMT5PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226814-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
US-20230127702-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-04-27 US disclosed