SCHEMBL26683030

SCHEMBL26683030

CN(C(=O)OC(C)(C)C)C1=C(/C=C/C2=[N+](CCCS(=O)(=O)O)c3ccc(Cl)cc3C2(C)C)CC/C1=C\C=C1\N(CCCS(=O)(=O)O)c2ccc(Cl)cc2C1(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.48
PRMT1 Q99873 4/20 0.46
PRMT5 O14744 1/20 0.38
CARM1 Q86X55 1/20 0.38
PRMT8 Q9NR22 1/20 0.38
FOLH1 Q04609 2/20 0.37
HTR1A P08908 3/20 0.37
CHRM1 P11229 2/20 0.37
CHRM3 P20309 2/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
FOLR1 P15328 6/20 0.36
MLNR O43193 1/20 0.35
NR1I2 O75469 1/20 0.35
PGR P06401 1/20 0.35
ADRB1 P08588 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
DRD2 P14416 1/20 0.35
ADRA2B P18089 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25862037 0.91 PTPN1 (0.47) PTPN1PRMT1PRMT5CARM1PRMT8
SCHEMBL25837259 0.90 PTPN1 (0.44) PTPN1PRMT1PRMT5CARM1PRMT8
SCHEMBL12414956 0.88 PTPN1 (0.49) PTPN1PRMT1PRMT5CARM1PRMT8
SCHEMBL12414957 0.88 PTPN1 (0.49) PTPN1PRMT1PRMT5CARM1PRMT8
SCHEMBL13100810 0.87 PRMT1 (0.43) PTPN1PRMT1PRMT5CARM1PRMT8
SCHEMBL13100870 0.86 HTR1A (0.48) PTPN1PRMT1FOLH1HTR1ACHRM1
SCHEMBL26683407 0.86 PTPN1 (0.56) PTPN1PRMT1PRMT5CARM1PRMT8
SCHEMBL13100809 0.86 PRMT1 (0.42) PTPN1PRMT1PRMT5CARM1PRMT8
SCHEMBL15436366 0.85 HTR1A (0.46) PTPN1PRMT1PRMT5CARM1PRMT8
SCHEMBL4753276 0.84 PTPN1 (0.46) PTPN1PRMT1PRMT5CARM1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4269122-A1 LAMINATE OF NEGATIVE LITHOGRAPHIC PRINTING PLATE ORIGINAL PLATE AND METHOD FOR MANUFACTURING NEGATIVE LITHOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2023-11-01 EP disclosed