SCHEMBL25837386

SCHEMBL25837386

Nc1nc(=O)n([C@H]2C[C@@H](O)C(CO)O2)cc1CO

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 8/20 0.64
ADRB1 P08588 1/20 0.63
DNMT3B Q9UBC3 3/20 0.61
FPR2 P25090 2/20 0.54
TK1 P04183 2/20 0.50
TK2 O00142 1/20 0.50
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
PNP P00491 1/20 0.49
TP53 P04637 1/20 0.49
HTT P42858 1/20 0.49
PDE4D Q08499 1/20 0.49
PDE3A Q14432 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29431942 1.00 DNMT1 (0.64) DNMT1ADRB1DNMT3BFPR2TK1
SCHEMBL22299584 1.00 DNMT1 (0.64) DNMT1ADRB1DNMT3BFPR2TK1
SCHEMBL231959 1.00 DNMT1 (0.64) DNMT1ADRB1DNMT3BFPR2TK1
SCHEMBL231960 1.00 DNMT1 (0.64) DNMT1ADRB1DNMT3BFPR2TK1
SCHEMBL17204628 0.95 DNMT1 (0.60) DNMT1ADRB1DNMT3BFPR2TK1
Phosphoric Acid SCHEMBL7744455 0.95 DNMT1 (0.63) DNMT1ADRB1DNMT3BFPR2TK1
Phosphoric Acid SCHEMBL15201232 0.95 DNMT1 (0.63) DNMT1ADRB1DNMT3BFPR2TK1
Pyrophosphoric Acid SCHEMBL14660971 0.92 DNMT1 (0.60) DNMT1ADRB1DNMT3BFPR2TK1
SCHEMBL9780849 0.92 DNMT1 (0.63) DNMT1ADRB1DNMT3BFPR2TK1
SCHEMBL5982018 0.92 DNMT1 (0.63) DNMT1ADRB1DNMT3BFPR2TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233879-A1 DEOXY- CYTIDINE DERIVATIVES FOR USE IN CANCER THERAPIES Hemispherian AS (NO) 2023-08-30 EP disclosed
EP-3917538-B1 DEOXY- CYTIDINE DERIVATIVES FOR USE IN CANCER THERAPIES HEMISPHERIAN AS (NO) 2023-07-12 EP disclosed