SCHEMBL231960

SCHEMBL231960

Nc1nc(=O)n([C@H]2CC(O)[C@@H](CO)O2)cc1CO

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 8/20 0.64
ADRB1 P08588 1/20 0.63
DNMT3B Q9UBC3 3/20 0.61
FPR2 P25090 2/20 0.54
TK1 P04183 2/20 0.50
TK2 O00142 1/20 0.50
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
PNP P00491 1/20 0.49
TP53 P04637 1/20 0.49
HTT P42858 1/20 0.49
PDE4D Q08499 1/20 0.49
PDE3A Q14432 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25837386 1.00 DNMT1 (0.64) DNMT1ADRB1DNMT3BFPR2TK1
SCHEMBL29431942 1.00 DNMT1 (0.64) DNMT1ADRB1DNMT3BFPR2TK1
SCHEMBL22299584 1.00 DNMT1 (0.64) DNMT1ADRB1DNMT3BFPR2TK1
SCHEMBL231959 1.00 DNMT1 (0.64) DNMT1ADRB1DNMT3BFPR2TK1
SCHEMBL17204628 0.95 DNMT1 (0.60) DNMT1ADRB1DNMT3BFPR2TK1
Phosphoric Acid SCHEMBL7744455 0.95 DNMT1 (0.63) DNMT1ADRB1DNMT3BFPR2TK1
Phosphoric Acid SCHEMBL15201232 0.95 DNMT1 (0.63) DNMT1ADRB1DNMT3BFPR2TK1
Pyrophosphoric Acid SCHEMBL14660971 0.92 DNMT1 (0.60) DNMT1ADRB1DNMT3BFPR2TK1
SCHEMBL9780849 0.92 DNMT1 (0.63) DNMT1ADRB1DNMT3BFPR2TK1
SCHEMBL5982018 0.92 DNMT1 (0.63) DNMT1ADRB1DNMT3BFPR2TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605397-B2 Deoxy-cytidine or uridine derivatives for use in cancer therapies TETRAGON BIOSCIENCE LTD. (IL) 2026-04-21 US claimed
EP-4640827-A1 RECOMBINANT TET3 ENZYMES Ludwig-Maximilians-Universität München (DE) 2025-10-29 EP claimed
US-20250313888-A1 ADAPTERS, METHODS, AND COMPOSITIONS FOR DUPLEX SEQUENCING TWINSTRAND BIOSCIENCES, INC. (US) 2025-10-09 US claimed
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
EP-4591940-A2 DEOXY- CYTIDINE DERIVATIVES FOR USE IN CANCER THERAPIES Hemispherian AS (NO) 2025-07-30 EP claimed
EP-4410993-A2 REAGENTS AND ADAPTERS FOR NUCLEIC ACID SEQUENCING AND METHODS FOR MAKING SUCH REAGENTS AND ADAPTERS Twinstrand Biosciences, Inc. (US) 2024-08-07 EP claimed
US-20240216415-A1 DEOXY-CYTIDINE OR URIDINE DERIVATIVES FOR USE IN CANCER THERAPIES TETRAGON BIOSCIENCES LTD. (IL) 2024-07-04 US claimed
CN-118078850-A Deoxycytidine or uridine derivatives for use in cancer treatment 赫米斯弗连有限公司 2024-05-28 CN claimed
US-11963973-B2 Deoxy-cytidine or uridine derivatives for use in cancer therapies HEMISPHERIAN AS (NO) 2024-04-23 US claimed
CN-113543789-B Deoxycytidine or uridine derivatives for use in cancer treatment 赫米斯弗连有限公司 2024-04-05 CN claimed
WO-2020157335-A1 DEOXY- CYTIDINE OR URIDINE DERIVATIVES FOR USE IN CANCER THERAPIES HEMISPHERIAN AS (NO) 2020-08-06 WO claimed
EP-3350343-B1 METHODS AND COMPOSITIONS FOR GENOMIC TARGET ENRICHMENT AND SELECTIVE DNA SEQUENCING PETAOMICS INC (US) 2020-04-22 EP claimed
EP-3387152-A1 IMPROVED ADAPTERS, METHODS, AND COMPOSITIONS FOR DUPLEX SEQUENCING Twinstrand Biosciences, Inc. (US) 2018-10-17 EP claimed
EP-3350343-A1 METHODS AND COMPOSITIONS FOR GENOMIC TARGET ENRICHMENT AND SELECTIVE DNA SEQUENCING Petaomics, Inc. (US) 2018-07-25 EP claimed
US-20170211140-A1 ADAPTERS, METHODS, AND COMPOSITIONS FOR DUPLEX SEQUENCING TWINSTRAND BIOSCIENCES, INC. 2017-07-27 US claimed
WO-2017100441-A1 IMPROVED ADAPTERS, METHODS, AND COMPOSITIONS FOR DUPLEX SEQUENCING TWINSTRAND BIOSCIENCES, INC. (US) 2017-06-15 WO claimed
WO-2017049213-A1 METHODS AND COMPOSITIONS FOR GENOMIC TARGET ENRICHMENT AND SELECTIVE DNA SEQUENCING PetaOmics, Inc. (US) 2017-03-23 WO claimed
US-8206935-B2 Method of rapidly quantifying hydroxymethylated DNA LI WEIWEI (US) 2012-06-26 US claimed
WO-2012016145-A2 MITOCHONDRIAL APOPTOSIS-INDUCED INFLAMMATION CEDARS-SINAI MEDICAL CENTER (US) 2012-02-02 WO claimed
US-20120003663-A1 Method of rapidly quantifying hydroxymethylated DNA LI WEIWEI (US) 2012-01-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT DNMT1 384/4885ADRB1 4067/4885DNMT3B 303/4885
US-11963973-B2 Deoxy-cytidine or uridine derivatives for use in cancer therapies UMPS, UPP1, TYMP DNMT1 697/4885ADRB1 1973/4885DNMT3B 1054/4885
US-20240216415-A1 DEOXY-CYTIDINE OR URIDINE DERIVATIVES FOR USE IN CANCER THERAPIES UMPS, UPP1, TYMP DNMT1 667/4885ADRB1 1969/4885DNMT3B 1007/4885
US-12605397-B2 Deoxy-cytidine or uridine derivatives for use in cancer therapies CDA, DCTD, RNMT DNMT1 268/4885ADRB1 1859/4885DNMT3B 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.