Phosphoric Acid

Phosphoric Acid

SCHEMBL7744455

Nc1nc(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1CO.O=P(O)(O)O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADRB1 known ✓ P08588 1/20 0.58
DNMT1 P26358 8/20 0.63
DNMT3B Q9UBC3 3/20 0.60
FPR2 P25090 2/20 0.51
TK2 O00142 1/20 0.47
TK1 P04183 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL15201232 1.00 DNMT1 (0.63) DNMT1DNMT3BADRB1FPR2TK2
SCHEMBL231959 0.95 DNMT1 (0.64) DNMT1DNMT3BADRB1FPR2TK2
SCHEMBL22299584 0.95 DNMT1 (0.64) DNMT1DNMT3BADRB1FPR2TK2
SCHEMBL29431942 0.95 DNMT1 (0.64) DNMT1DNMT3BADRB1FPR2TK2
SCHEMBL25837386 0.95 DNMT1 (0.64) DNMT1DNMT3BADRB1FPR2TK2
SCHEMBL231960 0.95 DNMT1 (0.64) DNMT1DNMT3BADRB1FPR2TK2
Pyrophosphoric Acid SCHEMBL14660971 0.95 DNMT1 (0.60) DNMT1DNMT3BADRB1FPR2TK2
Triphosphate SCHEMBL28135309 0.93 DNMT1 (0.58) DNMT1DNMT3BADRB1FPR2
SCHEMBL17204628 0.91 DNMT1 (0.60) DNMT1DNMT3BADRB1FPR2TK2
SCHEMBL1331043 0.88 TYMS (0.55) DNMT1DNMT3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125749-A1 HAIRPIN LOOP METHOD FOR DOUBLE STRAND POLYNUCLEOTIDE SEQUENCING USING TRANSMEMBRANE PORES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-07 US disclosed
US-12595509-B2 Synthetic nucleic acid spike-ins KARIUS, INC. (US) 2026-04-07 US disclosed
US-20260072019-A1 METHOD OF DETERMINING THE PRESENCE OR ABSENCE OF A TARGET ANALYTE COMPRISING USING A REPORTER POLYNUCLEOTIDE AND A TRANSMEMBRANE PORE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-12 US disclosed
US-12553085-B2 Sequencing kit OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-02-17 US disclosed
US-20260043809-A1 AFFINITY CAPTURE REAGENTS FOR MASS SPECTROMETRY UNIV OXFORD INNOVATION LTD (GB) 2026-02-12 US disclosed
US-20260028379-A1 MUTANT PORE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-01-29 US disclosed
US-12509721-B2 Methods and systems for characterizing analytes using nanopores OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-12-30 US disclosed
EP-4665753-A1 ARMOURED REGULATORY T CELL King's College London (GB) 2025-12-24 EP disclosed
US-20250361502-A1 Promoters And Compositions UNIV OXFORD INNOVATION LTD (GB) 2025-11-27 US disclosed
EP-3802877-B1 METHOD OXFORD NANOPORE TECH PLC (GB) 2025-11-05 EP disclosed
WO-2014102539-A1 DELIVERY METHOD USING MESOPOROUS SILICA NANOPARTICLES ISIS INNOVATION LIMITED (GB) 2014-07-03 WO disclosed
WO-2014072703-A1 QUADRUPLEX METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2014-05-15 WO disclosed
WO-2013153359-A1 MUTANT LYSENIN PORES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2013-10-17 WO disclosed
WO-2013121201-A1 APTAMER METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2013-08-22 WO disclosed
EP-0923591-A4 NOVEL BORONIC ACID-CONTAINING NUCLEIC ACIDS AND THEIR USE AS DIAGNOSTIC AGENTS PROLINX INC (US) 2001-01-31 EP disclosed
EP-0923591-A1 NOVEL BORONIC ACID-CONTAINING NUCLEIC ACIDS AND THEIR USE AS DIAGNOSTIC AGENTS PROLINX, INC. (US) 1999-06-23 EP disclosed
US-5876938-A Use of boron-containing polynucleotides as diagnostic agents PROLINX, INCORPORATED (US) 1999-03-02 US disclosed
US-5831045-A Boronic acid-containing polynucleotides PORLINX, INCORPORATED (US) 1998-11-03 US disclosed
US-5831046-A Boronic acid-contaning nucleic acid monomers PROLINX, INCORPORATED (US) 1998-11-03 US disclosed
WO-1998005672-A1 NOVEL BORONIC ACID-CONTAINING NUCLEIC ACIDS AND THEIR USE AS DIAGNOSTIC AGENTS PROLINX INCORPORATED (US) 1998-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260072019-A1 METHOD OF DETERMINING THE PRESENCE OR ABSENCE OF A TARGET ANALYTE COMPRISING USING A REPORTER POLYNUCLEOTIDE AND A TRANSMEMBRANE PORE NUP210, EPCAM, PHAX ADRB1 4010/4885DNMT1 2398/4885DNMT3B 2061/4885
US-12509721-B2 Methods and systems for characterizing analytes using nanopores DNA2, MTREX, DDX21 ADRB1 4774/4885DNMT1 123/4885DNMT3B 154/4885
US-20260043809-A1 AFFINITY CAPTURE REAGENTS FOR MASS SPECTROMETRY DDX6, DDX1, DDB1 ADRB1 4608/4885DNMT1 679/4885DNMT3B 735/4885
US-12553085-B2 Sequencing kit PHAX, TIA1, POLM ADRB1 4270/4885DNMT1 1190/4885DNMT3B 838/4885
US-20260125749-A1 HAIRPIN LOOP METHOD FOR DOUBLE STRAND POLYNUCLEOTIDE SEQUENCING USING TRANSMEMBRANE PORES POLRMT, PITPNB, NUP205 ADRB1 4063/4885DNMT1 959/4885DNMT3B 1043/4885
US-20260028379-A1 MUTANT PORE PTMS, NUP50, NUP205 ADRB1 4612/4885DNMT1 2912/4885DNMT3B 1770/4885
US-12595509-B2 Synthetic nucleic acid spike-ins SPOUT1, NOP2, METTL16 ADRB1 4785/4885DNMT1 818/4885DNMT3B 1622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.