Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
| ▸ | MIF | P14174 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25837994 | 0.95 | METAP1 (0.38) | METAP1MIFDRD2DRD1DRD5 | |
| SCHEMBL1817753 | 0.87 | METAP1 (0.39) | METAP1DRD2DRD1ALDH1A1ALOX15 | |
| SCHEMBL14267919 | 0.81 | MIF (0.45) | MIFALDH1A1CYP1A2HSD17B10MEN1 | |
| SCHEMBL15869786 | 0.76 | METAP1 (0.54) | METAP1DRD2DRD1DRD5DRD3 | |
| SCHEMBL20306054 | 0.76 | METAP1 (0.39) | METAP1DRD2DRD1ALDH1A1ALOX15 | |
| SCHEMBL27500150 | 0.75 | METAP1 (0.44) | METAP1MIFDRD2DRD1DRD5 | |
| SCHEMBL27482978 | 0.75 | METAP1 (0.44) | METAP1MIFDRD2DRD1DRD5 | |
| SCHEMBL9899477 | 0.75 | ESR1 (0.41) | CA1CA2CA4CA6MEN1 | |
| SCHEMBL26032670 | 0.73 | MAPT (0.37) | ALDH1A1MEN1KMT2ANPC1CASP3 | |
| SCHEMBL15483667 | 0.72 | METAP1 (0.63) | METAP1MIFDRD2DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023136213-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-20 | — | — | WO | disclosed |