SCHEMBL25837994

SCHEMBL25837994

COc1ccc2c3c(cc(O)c2c1)Cc1cc(C)ccc1-3

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 2/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.37
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
CASP3 P42574 2/20 0.36
SENP8 Q96LD8 2/20 0.36
SENP7 Q9BQF6 2/20 0.36
SENP6 Q9GZR1 2/20 0.36
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MIF P14174 1/20 0.36
DRD2 P14416 1/20 0.35
DRD1 P21728 1/20 0.35
DRD5 P21918 1/20 0.35
DRD3 P35462 1/20 0.35
MAPT P10636 3/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25837953 0.95 METAP1 (0.40) METAP1MEN1KMT2AALDH1A1HPGD
SCHEMBL1817753 0.87 METAP1 (0.39) METAP1MEN1KMT2AALDH1A1NPC1
SCHEMBL14267919 0.81 MIF (0.45) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL9899477 0.78 ESR1 (0.41) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL15869786 0.76 METAP1 (0.54) METAP1MEN1KMT2AALDH1A1HPGD
SCHEMBL26032670 0.75 MAPT (0.37) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL25954042 0.73 MAPT (0.34) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL20306054 0.73 METAP1 (0.39) METAP1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL26452512 0.72 MAPT (0.33) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL27500150 0.72 METAP1 (0.44) METAP1ALDH1A1MIFDRD2DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023136213-A1 PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES 株式会社トクヤマ 2023-07-20 WO disclosed