Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 19/20 | 0.69 |
| ▸ | MET | P08581 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24006228 | 0.91 | KDR (0.71) | KDRMETKDM4EMEN1ALDH1A1 | |
| SCHEMBL24003904 | 0.91 | KDR (0.71) | KDRMETKDM4EMEN1ALDH1A1 | |
| SCHEMBL25820956 | 0.91 | KDR (0.77) | KDRMET | |
| SCHEMBL25455011 | 0.83 | KDR (0.71) | KDRMETKDM4EMEN1ALDH1A1 | |
| SCHEMBL24006212 | 0.83 | KDR (0.73) | KDRMETKDM4EALDH1A1HPGD | |
| SCHEMBL23999470 | 0.83 | KDR (0.73) | KDRMETKDM4EALDH1A1HPGD | |
| SCHEMBL24009926 | 0.81 | KDR (0.61) | KDRMET | |
| SCHEMBL24010184 | 0.79 | KDR (0.49) | KDR | |
| SCHEMBL25826862 | 0.78 | KDR (0.68) | KDRMET | |
| SCHEMBL24003905 | 0.78 | KDR (0.58) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | KDR 2851/4885MET 1110/4885KDM4E 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.