SCHEMBL25838246

SCHEMBL25838246

COCCCC1(CCCOC)c2ccccc2-c2c1c1c(c3cc(OC)c(Br)cc23)OC(c2ccc(N3CCOCC3)cc2)(c2ccc(OC)c(OC)c2)C=C1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.30
ALDH1A1 P00352 2/20 0.30
MAPT P10636 2/20 0.30
KMT2A Q03164 2/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25838265 0.91 ACHE (0.31) ALDH1A1MAPT
SCHEMBL25605185 0.84 STK10 (0.35) MEN1ALDH1A1MAPTKMT2A
SCHEMBL26628853 0.83 STK10 (0.34) MEN1ALDH1A1MAPTKMT2A
SCHEMBL25836580 0.83 PRKDC (0.34) MEN1ALDH1A1MAPTKMT2A
SCHEMBL25836574 0.83 PRKDC (0.34) MEN1ALDH1A1MAPTKMT2A
SCHEMBL25836567 0.82 EGFR (0.32) MEN1ALDH1A1KMT2A
SCHEMBL26630043 0.82 STK10 (0.33) MEN1ALDH1A1MAPTKMT2A
SCHEMBL25599968 0.82 STK10 (0.33) MEN1ALDH1A1MAPTKMT2A
SCHEMBL25599864 0.82 RAB9A (0.34) MEN1ALDH1A1MAPTKMT2A
SCHEMBL3692658 0.81 STK10 (0.32) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023136213-A1 PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES 株式会社トクヤマ 2023-07-20 WO disclosed