Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | BAD | Q92934 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 3/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25838305 | 0.88 | KDM4E (0.38) | PDE4BPLA2G1BMAPTATG4BSPR | |
| SCHEMBL25838297 | 0.84 | PDE4B (0.32) | PDE4BPLA2G1BMAPTATG4BSPR | |
| SCHEMBL25838291 | 0.84 | HSP90AA1 (0.33) | PDE4BPOLBHSP90AA1HSP90AB1 | |
| SCHEMBL25300385 | 0.82 | MAP3K12 (0.36) | — | |
| SCHEMBL30068705 | 0.82 | MAP3K12 (0.36) | — | |
| SCHEMBL25300384 | 0.82 | MAP3K12 (0.36) | — | |
| SCHEMBL25837869 | 0.81 | PROKR1 (0.38) | PDE4BMAPTMAPK1KDM2B | |
| SCHEMBL25838318 | 0.80 | SPR (0.35) | SPRCFTRMAPK1HSP90AA1HSP90AB1 | |
| SCHEMBL25838322 | 0.79 | HSP90AA1 (0.33) | PDE4BMAPK1HSD17B10HSP90AA1HSP90AB1 | |
| SCHEMBL25837868 | 0.79 | LMNA (0.36) | PDE4BPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |