Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP19 | O94966 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25838327 | 0.88 | PRMT5 (0.32) | — | |
| SCHEMBL25838331 | 0.88 | PRMT5 (0.32) | — | |
| SCHEMBL25838324 | 0.84 | LMNA (0.40) | ALDH1A1 | |
| SCHEMBL25838184 | 0.80 | ADRA1A (0.31) | — | |
| SCHEMBL25838185 | 0.79 | PRMT5 (0.33) | — | |
| SCHEMBL25838456 | 0.78 | PLAT (0.33) | — | |
| SCHEMBL25838489 | 0.78 | — | — | |
| SCHEMBL25837882 | 0.77 | DPP4 (0.40) | ALDH1A1HPGDMAPK1 | |
| SCHEMBL25838487 | 0.77 | HSD17B10 (0.32) | — | |
| SCHEMBL25837881 | 0.77 | MAPK1 (0.33) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |