Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 16/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | CCNK | O75909 | 1/20 | 0.47 |
| ▸ | CCND3 | P30281 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21446898 | 0.88 | AXL (0.69) | AXLAURKBAURKAALKJAK2 | |
| SCHEMBL25838418 | 0.82 | AXL (0.66) | AXLAURKBAURKAALKJAK2 | |
| SCHEMBL31173516 | 0.80 | AXL (0.80) | AXLAURKBAURKAALKJAK2 | |
| SCHEMBL25840157 | 0.80 | AXL (0.80) | AXLAURKBAURKAALKJAK2 | |
| SCHEMBL21446888 | 0.79 | AXL (0.57) | AXLAURKBAURKAALKJAK2 | |
| SCHEMBL24073135 | 0.79 | AXL (0.70) | AXLAURKBAURKAALKJAK2 | |
| SCHEMBL25837702 | 0.77 | AXL (0.80) | AXLAURKBAURKAALKJAK2 | |
| SCHEMBL25838551 | 0.76 | AXL (0.62) | AXLAURKBAURKAALKJAK2 | |
| SCHEMBL25839353 | 0.76 | AXL (0.62) | AXLAURKBAURKAALKJAK2 | |
| SCHEMBL21446891 | 0.75 | AXL (0.53) | AXLAURKBAURKAALKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134582-A1 | PYRIMIDINE-2,4-DIAMINE DERIVATIVES AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | 上海立森印迹医药技术有限公司 | 2023-07-20 | — | — | WO | disclosed |