Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25838495 | 0.82 | KCNH2 (0.33) | HSD17B10 | |
| SCHEMBL25837980 | 0.80 | HSD17B10 (0.33) | HSD17B10 | |
| SCHEMBL25258943 | 0.79 | MAP3K12 (0.42) | — | |
| SCHEMBL30068859 | 0.79 | MAP3K12 (0.42) | — | |
| SCHEMBL25839713 | 0.74 | — | — | |
| SCHEMBL25838285 | 0.72 | CHRM2 (0.37) | HSD17B10 | |
| SCHEMBL25302375 | 0.72 | MAP3K12 (0.42) | — | |
| SCHEMBL30068624 | 0.72 | MAP3K12 (0.42) | — | |
| SCHEMBL25302377 | 0.72 | MAP3K12 (0.42) | — | |
| SCHEMBL25837969 | 0.70 | CHRM2 (0.40) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |