Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | RBP4 | P02753 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25838497 | 0.80 | THRB (0.33) | HSD17B10 | |
| SCHEMBL30491229 | 0.78 | PIK3CG (0.41) | CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25299524 | 0.78 | PIK3CG (0.41) | CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25299525 | 0.78 | PIK3CG (0.41) | CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25837964 | 0.75 | PDK2 (0.42) | — | |
| SCHEMBL25837977 | 0.74 | NAMPT (0.33) | HSD17B10CYP1A2CYP2D6PRMT5WDR77 | |
| SCHEMBL25837882 | 0.74 | DPP4 (0.40) | MEN1KMT2ACYP1A2CYP3A4PRMT5 | |
| SCHEMBL25838495 | 0.73 | KCNH2 (0.33) | HSD17B10MEN1KMT2AKDM4ETP53 | |
| SCHEMBL25838280 | 0.71 | CREBBP (0.32) | HSD17B10 | |
| SCHEMBL25837978 | 0.70 | HSD17B10 (0.33) | HSD17B10MEN1KMT2AKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |