SCHEMBL25838914

SCHEMBL25838914

COC(=O)C/C=C/C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.40
CYP4F2 P78329 2/20 0.39
CYP4A11 Q02928 2/20 0.39
HSD17B10 Q99714 1/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
TET2 Q6N021 1/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 2/20 0.35
RECQL P46063 1/20 0.34
CYP2C19 P33261 2/20 0.34
CYP2C9 P11712 1/20 0.34
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CA12 O43570 2/20 0.31
CA14 Q9ULX7 2/20 0.31
CA2 P00918 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30505577 1.00 TSHR (0.40) TSHRCYP4F2CYP4A11HSD17B10MGAM
SCHEMBL11575575 0.81 TSHR (0.36) TSHRCYP4F2CYP4A11HSD17B10MGAM
SCHEMBL869082 0.80 TSHR (0.53) TSHRCYP4F2CYP4A11HSD17B10MGAM
SCHEMBL869080 0.80 TSHR (0.53) TSHRCYP4F2CYP4A11HSD17B10MGAM
SCHEMBL821076 0.80 TSHR (0.53) TSHRCYP4F2CYP4A11HSD17B10MGAM
SCHEMBL14885234 0.78 GAA (0.44) TSHRHSD17B10MGAMGAASI
SCHEMBL11941368 0.74 TSHR (0.37) TSHRCYP4F2CYP4A11HSD17B10MGAM
SCHEMBL25304685 0.73 CYP2D6 (0.55) TSHRHSD17B10ALDH1A1RECQLCYP2C19
SCHEMBL1784127 0.73 ALDH1A1 (0.32) ALDH1A1
SCHEMBL36817 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230223869-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C-Motive Technologies, Inc. (US) 2023-07-13 US claimed
US-20230223869-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C-Motive Technologies, Inc. (US) 2023-07-13 US disclosed