SCHEMBL258394

SCHEMBL258394

CO[PH](=O)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.38
TSHR P16473 2/20 0.36
PDE4B Q07343 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
ALDH1A1 P00352 3/20 0.32
KCNN4 O15554 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
KDM4E B2RXH2 2/20 0.32
LMNA P02545 2/20 0.32
LTA4H P09960 1/20 0.32
MAP2K7 O14733 1/20 0.32
GMNN O75496 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258348 0.97 CA4 (0.36) CA4TSHRPDE4BCA12CA1
SCHEMBL258618 0.97 CA4 (0.36) CA4TSHRPDE4BCA12CA1
SCHEMBL258478 0.97 CA4 (0.36) CA4TSHRPDE4BCA12CA1
SCHEMBL258292 0.97 CA4 (0.36) CA4TSHRPDE4BCA12CA1
Phenol SCHEMBL27580078 0.89 CA12 (0.46) CA4TSHRPDE4BCA12CA1
SCHEMBL191791 0.83
SCHEMBL190026 0.83
SCHEMBL258150 0.83
SCHEMBL3666357 0.82 CA4 (0.36) CA4TSHRPDE4BCA12CA1
SCHEMBL22499918 0.80 ALDH1A1 (0.52) TSHRALDH1A1KMT2ALMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025060129-A1 AMMONIUM DIHYDROCARBYLPHOSPHINATE AND PREPARATION METHOD THEREFOR AND USE THEREOF 江苏利思德新材料股份有限公司 2025-03-27 WO claimed
CN-114478624-B Telomer of diethyl aluminum phosphinate and preparation method thereof 兰州瑞朴科技有限公司 2024-07-02 CN claimed
CN-113698917-B Cooling liquid composition for hydrogen fuel cell vehicle 统一石油化工有限公司 2023-11-24 CN claimed
CN-116715698-A Preparation method of 6-phosphoryl 1,2, 4-triazine-3, 5 (2H, 4H) -diketone derivative 河北工业大学 2023-09-08 CN claimed
CN-114149590-B Production process of polyether amide elastomer 无锡殷达尼龙有限公司 2022-12-02 CN claimed
CN-114621586-A Flame-retardant bio-based polyamide material and preparation method thereof 广东泰塑新材料科技有限公司 2022-06-14 CN claimed
CN-114478624-A Telomer of aluminum diethylphosphinate and preparation method thereof 兰州瑞朴科技有限公司 2022-05-13 CN claimed
CN-114181250-A Alkenyl phosphine compound and preparation method thereof 中国石油化工股份有限公司 2022-03-15 CN claimed
CN-114149590-A Production process of polyether amide elastomer 无锡殷达尼龙有限公司 2022-03-08 CN claimed
CN-113698917-A Cooling liquid composition for hydrogen fuel cell vehicle 统一石油化工有限公司 2021-11-26 CN claimed
CN-111117225-A Flame-retardant bio-based polyamide material and preparation method thereof 广东泰塑新材料科技有限公司 2020-05-08 CN claimed
CN-104487462-B Photopolymerization method and novel compound used for the same 拉姆博松有限公司 2016-11-23 CN claimed
US-8633127-B2 Selective hydrogenation catalyst and methods of making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-01-21 US claimed
US-8293862-B2 Polyester polymerization catalyst, polyester produced by using the same, and a process for producing polyester TOYO BOSEKI KABUSHIKI KAISHA (JP) 2012-10-23 US claimed
US-20070149757-A1 POLYESTER POLYMERIZATION CATALYST, POLYESTER PRODUCED BY USING THE SAME, AND A PROCESS FOR PRODUCING POLYESTER TOYO BOSEKI KABUSHIKI KAISHA (JP) 2007-06-28 US claimed
CN-1238423-C Thermoplastic resin composition and molded object thereof POLYPLASTICS CO (JP) 2006-01-25 CN claimed
EP-0469354-B1 Flame-resistant polyolefinic fibres and films GREAT LAKES CHEMICAL ITALIA (IT) 1996-12-04 EP claimed
US-5447991-A Copolyester blend containing phenyl hydroxymethylenephosphinic acid ENICHEM SYNTHESIS S.P.A. (IT) 1995-09-05 US claimed
EP-0469354-A2 Flame-resistant polyolefinic fibres and films GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) 1992-02-05 EP claimed
US-4044053-A Preparation of polyalkylene polyamines TEXACO DEVELOPMENT CORPORATION (US) 1977-08-23 US claimed