SCHEMBL258478

SCHEMBL258478

CO[PH](=O)c1ccccc1.[AlH3]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.36
TSHR P16473 1/20 0.34
PDE4B Q07343 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
ALDH1A1 P00352 3/20 0.31
KCNN4 O15554 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2C19 P33261 2/20 0.31
LTA4H P09960 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAP2K7 O14733 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258394 0.97 CA4 (0.38) CA4TSHRPDE4BCA12CA1
SCHEMBL258292 0.95 CA4 (0.36) CA4TSHRPDE4BCA12CA1
SCHEMBL258618 0.95 CA4 (0.36) CA4TSHRPDE4BCA12CA1
SCHEMBL258348 0.95 CA4 (0.36) CA4TSHRPDE4BCA12CA1
SCHEMBL258150 0.87
Phenol SCHEMBL27580078 0.87 CA12 (0.46) CA4TSHRPDE4BCA12CA1
SCHEMBL190026 0.81
SCHEMBL191791 0.81
SCHEMBL3666357 0.80 CA4 (0.36) CA4TSHRPDE4BCA12CA1
SCHEMBL22499918 0.78 ALDH1A1 (0.52) TSHRALDH1A1KMT2ACYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115216142-B Antistatic halogen-free flame-retardant reinforced nylon composite material and preparation method thereof 横店集团得邦工程塑料有限公司 2023-07-18 CN claimed
CN-115304913-B Reinforced flame-retardant hypophosphite/nylon composite material with high glow wire ignition temperature and preparation method thereof 横店集团得邦工程塑料有限公司 2023-07-18 CN disclosed
CN-112795183-B High-strength, low-shrinkage and low-precipitation environment-friendly flame-retardant polyamide composition and preparation method thereof 上海普利特复合材料股份有限公司 2023-02-21 CN disclosed
CN-112795183-A High-strength, low-shrinkage and low-precipitation environment-friendly flame-retardant polyamide composition and preparation method thereof 上海普利特复合材料股份有限公司 2021-05-14 CN disclosed
CN-112608592-A High-dispersibility high-concentration nylon-based halogen-free flame-retardant master batch and preparation method thereof 浙江旭森非卤消烟阻燃剂有限公司 2021-04-06 CN disclosed
CN-104558690-A Organosilicon-coating-modified hypophosphite/phosphate flame retardant UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-04-29 CN disclosed
US-8053500-B2 Flame-retardant polyamide resin composition and molded article MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2011-11-08 US disclosed
EP-2100919-B1 FLAME-RETARDANT POLYAMIDE RESIN COMPOSITION AND MOLDED ARTICLE MITSUBISHI ENG PLASTICS CORP (JP) 2011-03-09 EP disclosed
US-20100069539-A1 FLAME-RETARDANT POLYAMIDE RESIN COMPOSITION AND MOLDED ARTICLE MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2010-03-18 US disclosed
EP-2100919-A1 FLAME-RETARDANT POLYAMIDE RESIN COMPOSITION AND MOLDED ARTICLE Mitsubishi Engineering-Plastics Corporation (JP) 2009-09-16 EP disclosed