SCHEMBL25839568 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	AXL	P30530	11/20	0.50

▸	AURKB	Q96GD4	2/20	0.48

▸	AURKA	O14965	1/20	0.48

▸	ALK	Q9UM73	3/20	0.47

▸	JAK2	O60674	1/20	0.47

▸	IGF1R	P08069	1/20	0.47

▸	CCNK	O75909	2/20	0.47

▸	CCNA2	P20248	2/20	0.47

▸	CDK2	P24941	2/20	0.47

▸	CCND3	P30281	2/20	0.47

▸	CDK9	P50750	2/20	0.47

▸	CDK6	Q00534	2/20	0.47

▸	PTK2	Q05397	2/20	0.47

▸	EGFR	P00533	1/20	0.47

▸	MAP3K7	O43318	2/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21446898	0.84	AXL (0.69)	AXLAURKBAURKAALKJAK2
SCHEMBL25837787	0.83	ALK (0.60)	AXLAURKBAURKAALKJAK2
SCHEMBL25837703	0.81	AXL (0.74)	AXLAURKBAURKAALKIGF1R
SCHEMBL25839528	0.81	PTK2 (0.52)	AXLAURKAALKJAK2CCNK
SCHEMBL21446888	0.81	AXL (0.57)	AXLAURKBAURKAALKJAK2
SCHEMBL25838868	0.77	AXL (0.53)	AXLAURKBAURKAALKJAK2
SCHEMBL21446891	0.77	AXL (0.53)	AXLAURKBAURKAALKJAK2
SCHEMBL24073135	0.73	AXL (0.70)	AXLAURKBAURKAALKJAK2
SCHEMBL25838410	0.73	AXL (0.58)	AXLAURKBAURKAALKJAK2
SCHEMBL25838913	0.73	AXL (0.54)	AXLAURKBAURKAALKJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023134582-A1	PYRIMIDINE-2,4-DIAMINE DERIVATIVES AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF	上海立森印迹医药技术有限公司	2023-07-20	—	—	WO	disclosed