Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25845852 | 0.83 | SLC6A2 (0.49) | GRIN1GRIN2BCHRNB4CHRNA3PDE9A | |
| SCHEMBL20147427 | 0.79 | CHRNB2 (0.50) | CHRNB2CHRNA4GRIN1GRIN2BCHRNB4 | |
| SCHEMBL21185143 | 0.75 | CHRNB2 (0.55) | CHRNB2CHRNA4GRIN1GRIN2BCHRNA3 | |
| SCHEMBL25845855 | 0.74 | HCRTR1 (0.42) | PDE9AHRH3 | |
| SCHEMBL6311007 | 0.74 | OGA (0.53) | CHRNB2CHRNA4CHRNB4CHRNA3PDE9A | |
| SCHEMBL20147421 | 0.73 | OGA (0.57) | CHRNB2CHRNA4CHRNB4CHRNA3OGA | |
| SCHEMBL31680727 | 0.73 | CHRNB2 (0.54) | CHRNB2CHRNA4GRIN1GRIN2BCHRNB4 | |
| SCHEMBL12819481 | 0.73 | CHRNB2 (0.54) | CHRNB2CHRNA4GRIN1GRIN2BCHRNB4 | |
| SCHEMBL30471948 | 0.71 | CHRNB2 (0.55) | CHRNB2CHRNA4GRIN1GRIN2BCHRNB4 | |
| SCHEMBL31276985 | 0.70 | CHRNB2 (0.67) | CHRNB2CHRNA4CHRNB4CHRNA3OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125825-A1 | ANTICORONVIRAL COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SHANGHAI CUREGENE PHARMACEUTICAL CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |