Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14877504 | 0.81 | HCRTR2 (0.44) | HCRTR1HCRTR2KDM5ANAAAHRH3 | |
| SCHEMBL2737396 | 0.79 | KDM5A (0.45) | HCRTR1HCRTR2KDM5ANAAAHRH3 | |
| SCHEMBL25845852 | 0.78 | SLC6A2 (0.49) | NAAAHRH3PDE9A | |
| SCHEMBL8291705 | 0.76 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL20147430 | 0.74 | HRH3 (0.52) | HCRTR1HCRTR2KDM5ANAAAHRH3 | |
| SCHEMBL25839756 | 0.74 | CHRNB2 (0.45) | HRH3PDE9A | |
| SCHEMBL21185144 | 0.74 | FURIN (0.45) | HCRTR1HCRTR2KDM5ANAAAHRH3 | |
| SCHEMBL19111213 | 0.74 | HRH3 (0.57) | KDM5AHRH3PDE3BPDE3APDE10A | |
| SCHEMBL31143611 | 0.72 | NAAA (0.44) | HCRTR1HCRTR2KDM5ANAAAHRH3 | |
| SCHEMBL2760245 | 0.72 | PDE3B (0.43) | HCRTR1HCRTR2KDM5ANAAAPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125825-A1 | ANTICORONVIRAL COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SHANGHAI CUREGENE PHARMACEUTICAL CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |