SCHEMBL25840624

SCHEMBL25840624

Sc1ccc2ccc3ccc(Sc4cccc5c4ccc4ccccc45)cc3c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 0.41
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 3/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
SIRT3 Q9NTG7 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
CYP2A6 P11509 1/20 0.35
TSHR P16473 1/20 0.35
CYP1A2 P05177 2/20 0.35
HPGD P15428 1/20 0.35
IFNAR1 P17181 1/20 0.33
ERBB2 P04626 1/20 0.33
FYN P06241 1/20 0.33
MAOA P21397 1/20 0.33
ACHE P22303 1/20 0.33
AHR P35869 1/20 0.33
CTSD P07339 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23521034 0.84 HPRT1 (0.42) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL20391642 0.80 HPRT1 (0.64) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL23521032 0.79 HPRT1 (0.32) HPRT1
SCHEMBL22984562 0.78 HPRT1 (0.36) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL31301353 0.77 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL30544440 0.77 HPRT1 (0.64) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL2944062 0.77 HPRT1 (0.64) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL10785261 0.77 ALDH1A1 (0.64) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL12473667 0.73 HPRT1 (0.64) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL21693350 0.71 ALDH1A1 (0.61) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226814-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed