SCHEMBL2944062

SCHEMBL2944062

c1ccc2c(c1)ccc1c(Sc3cccc4c3ccc3ccccc34)cccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 0.64
ALDH1A1 P00352 5/20 0.55
HSD17B10 Q99714 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
CYP2A6 P11509 1/20 0.55
TSHR P16473 1/20 0.55
IFNAR1 P17181 1/20 0.49
LMNA P02545 3/20 0.47
MAPK1 P28482 3/20 0.47
NPY1R P25929 1/20 0.47
NPY2R P49146 1/20 0.47
PAX8 Q06710 1/20 0.46
CYP1A2 P05177 2/20 0.46
HIF1A Q16665 1/20 0.46
CYP1B1 Q16678 1/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
MAPT P10636 2/20 0.42
CYP3A4 P08684 1/20 0.42
APEX1 P27695 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30544440 1.00 HPRT1 (0.64) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL31301353 0.88 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL1394585 0.86 HPRT1 (0.64) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL31167972 0.85 IFNAR1 (0.60) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL577858 0.85 IFNAR1 (0.60) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL30548749 0.83 IFNAR1 (0.58) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL8812298 0.83 HPRT1 (0.58) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
Chrysene SCHEMBL384031 0.80 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL31177955 0.80 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL25510 0.80 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TDP1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871855-B2 Terminally unsaturated polyolefin and method for producing the same IDEMITSU KOSAN CO., LTD. (JP) 2014-10-28 US disclosed
US-20140194637-A1 A-OLEFIN OLIGOMER AND PRODUCTION METHOD THEREOF IDEMITSU KOSAN CO., LTD. (JP) 2014-07-10 US disclosed
EP-2746302-A1 OLEFIN OLIGOMER AND PRODUCTION METHOD THEREOF Idemitsu Kosan Co., Ltd (JP) 2014-06-25 EP disclosed
EP-2578607-A1 TERMINALLY UNSATURATED POLYOLEFIN, AND MANUFACTURING METHOD THEREOF Idemitsu Kosan Co., Ltd. (JP) 2013-04-10 EP disclosed
US-20130066007-A1 TERMINALLY UNSATURATED POLYOLEFIN AND METHOD FOR PRODUCING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-03-14 US disclosed
EP-1867662-B2 Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same IDEMITSU KOSAN CO (JP) 2013-02-27 EP disclosed
EP-1231236-B1 POLYPROPYLENE FILM AND MULTILAYERED LAMINATE IDEMITSU KOSAN CO (JP) 2012-12-05 EP disclosed
US-20100324242-A1 HIGHLY PURE, TERMINAL-UNSATURATED OLEFIN POLYMER AND PROCESS FOR PRODUCTION THEREOF IDEMITSU KOSAN CO., LTD. (JP) 2010-12-23 US disclosed
EP-2028198-B1 Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containinig the same IDEMITSU KOSAN CO (JP) 2010-01-06 EP disclosed
EP-1710247-B1 TRANSITION METAL COMPOUND AND CATALYST FOR OLEFIN POLYMERIZATION IDEMITSU KOSAN CO (JP) 2009-10-21 EP disclosed
EP-1524278-A1 PROPYLENE POLYMER, AND RESIN COMPOSITION AND MOLDED PRODUCT THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 2005-04-20 EP disclosed
US-6770355-B1 USABLE AS A SUBSTITUTE FOR SOFT VINYL CHLORIDE FILMS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-08-03 US disclosed
US-6734270-B1 Polypropylene-based calendered article and injection-molded article IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-05-11 US disclosed
US-6730626-B2 TRANSITION METAL DERIVATIVE CAN REACT TO FORM AN IONIC COMPLEX WITH THE ALUMINOXANE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-05-04 US disclosed
EP-1323723-A1 TRANSITION METAL COMPOUNDS, POLYMERIZATION CATALYSTS FOR OLEFINS, OLEFIN POLYMERS AND PROCESS FOR THEIR PRODUCTION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-07-02 EP disclosed
US-20020193536-A1 Transition metal compound, polymerization catalysts for olefins, olefin polymers and process for their production IDEMITSU KOSAN CO. LTD. (JP) 2002-12-19 US disclosed
EP-1241206-A1 POLYPROPYLENE FILM AND MULTILAYERED LAMINATE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-09-18 EP disclosed
EP-1231236-A1 POLYPROPYLENE FILM AND MULTILAYERED LAMINATE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-08-14 EP disclosed
EP-1231226-A1 ROLLED POLYPROPYLENE AND INJECTION-MOLDED POLYPROPYLENE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-08-14 EP disclosed
EP-1227112-A1 PROPYLENE POLYMERS AND RESIN COMPOSITION AND MOLDING CONTAINING THE POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-07-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193536-A1 Transition metal compound, polymerization catalysts for olefins, olefin polymers and process for their production CCNE2, PYM1, AP1M1 HPRT1 1992/4885ALDH1A1 2755/4885HSD17B10 2121/4885
US-20140194637-A1 A-OLEFIN OLIGOMER AND PRODUCTION METHOD THEREOF SPIN3, SPIN1, SPIN4 HPRT1 3978/4885ALDH1A1 3663/4885HSD17B10 1956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.